Bioinformatics Research Associate (Functional Genomics)

Location: Oxford Road, Manchester, United Kingdom

Company

hirify.global research centre working on genetics, genomics, and osteoarthritis research.

What you will do

• Perform statistical and bioinformatic analyses of high-throughput genomics and functional genomics experiments in large patient cohorts.
• Analyze Hi-C, CUT&RUN, ATAC-seq, RNA-seq, and single-cell RNA-seq data.
• Develop and apply pipelines for multi-omics data integration and functional annotation of GWAS variants.
• Develop functionally weighted polygenic risk scores.
• Plan and manage multiple projects while contributing to conference abstracts, presentations, and peer-reviewed publications.

Requirements

• Hold or be close to obtaining a PhD in functional genomics or bioinformatics.
• Strong theoretical knowledge of functional genomics, epigenetics, and regulation of gene expression.
• Proven experience analyzing and interpreting genomics data, including Hi-C, ATAC-seq, RNA-seq, or CUT&RUN.
• Experience with Linux, Python, and R.
• Excellent interpersonal and communication skills, with the ability to collaborate with colleagues at all levels.

Nice to have

• Experience with multi-omics integration and functional annotation of GWAS variants.
• Experience generating polygenic risk scores or analyzing single-cell RNA-seq data.
• Knowledge of public human epigenomic resources such as Roadmap, Blueprint, and ENCODE.
• Experience with statistics.

Culture & Benefits

• Employer contribution pension.
• 29 days of annual leave plus bank holidays and Christmas closure.
• Ride-to-work and electric vehicle car schemes.
• Open research environment focused on education, learning, community, diversity, and debate.

Hiring process

• Applications close at midnight on the closing date.
• Shortlisting and interviews are handled as part of the recruitment process.