Senior Scientist (Gene Editing Process Sciences)

TL;DR

Senior Scientist (Gene Editing Process Sciences): Developing and improving gene editing and gene delivery materials for allogeneic CAR T cell therapies with an accent on process development, analytical development, and GMP manufacturing readiness. Focus on designing experiments, characterizing processes, developing control strategies, and troubleshooting manufacturing activities with internal teams and external CDMOs.

Location: Onsite in South San Francisco, California; candidates must be authorized to work in the United States. Travel of up to 10% is required.

Salary: $60–$70 per hour, equivalent to approximately $9,600–$11,200 per month based on 160 hours.

Company

hirify.global is a clinical-stage biotechnology company developing off-the-shelf allogeneic CAR T cell therapies for cancer and autoimmune diseases.

What you will do

• Provide technical leadership for the development and improvement of gene editing and gene delivery materials used in allogeneic cell therapies.
• Support internal teams and external CDMOs with process and analytical development expertise.
• Contribute to process characterization, control strategy development, PPQ planning, and commercial manufacturing readiness.
• Plan, execute, and troubleshoot process development and GMP manufacturing runs at CDMOs.
• Develop experiments and analytical assays to assess the impact of gene editing and gene delivery materials on CAR T production.
• Partner with R&D, External Manufacturing, MSAT, Quality, and other cross-functional stakeholders.

Requirements

• PhD in biological sciences, engineering, or a related discipline with 5+ years of relevant experience; alternatively, MS with 10+ years or BS with 12+ years of industry experience.
• Hands-on experience in process and analytical development or manufacturing of gene editing materials and/or viral or non-viral gene delivery materials.
• Experience applying Design of Experiments, statistical analysis, and data visualization tools such as JMP or Spotfire.
• Knowledge of cGMP manufacturing and regulatory expectations for biologics, gene editing materials, or cell therapy products.
• Must be authorized to work in the United States and able to work onsite in South San Francisco.
• Strong communication, organizational, prioritization, and independent working skills in a matrixed environment.

Nice to have

• Experience providing technical support to internal and external teams managing process development and manufacturing at CDMOs.

Culture & Benefits

• Collaborative environment with cross-functional work across process development, manufacturing, quality, and research teams.
• One-year contract with the possibility of extension or contract-to-hire.
• Annual performance bonus and equity.
• Health insurance and generous paid time off, including two company-wide holiday shutdowns.