обновлено 11 дней назад
Director of Chemistry (Small Molecule Process Development and Manufacturing)
188 000 - 259 000$
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Director of Chemistry (Small Molecule Process Development and Manufacturing) (Biotech/Pharmaceutical Process Chemistry): Leading scientific and engineering teams in the design, optimization, characterization, and manufacturing transfer of robust small-molecule processes for preclinical and clinical medicines with an accent on process understanding, safety, productivity, and CMC support. Focus on scaling chemical and biochemical processes, developing impurity controls and phase-appropriate knowledge packages, and guiding cross-functional teams toward regulatory filings and clinical supply.
Location: Cambridge, Massachusetts, United States
Base compensation: $188,000–$259,000 per year
Company
is a biotechnology company developing life-changing medicines across multiple drug modalities.
What you will do
- Lead scientific, engineering, development, and manufacturing teams through early- to late-phase small-molecule drug development.
- Design and guide experiments to optimize and characterize chemical processes, improving process understanding, robustness, productivity, safety, and cost effectiveness.
- Develop fundamental process knowledge for transferring chemical and biochemical processes from laboratory scale to manufacturing partners.
- Collaborate with Process Engineering, Analytical Chemistry, Oligo Synthesis, Solid Form, and Separations functions to establish process controls and support clinical material supply.
- Manage and mentor scientific colleagues while developing future scientific and engineering leaders.
- Communicate research results, contribute to CMC activities and IND sections, engage with contract research organizations, and represent the organization at conferences and consortia.
Requirements
- M.S. or Ph.D. with 12+ years of relevant pharmaceutical or biotechnology experience, including people management.
- Strong expertise in pharmaceutical process chemistry and engineering, including synthetic strategies, impurity controls, analytical methods, purification, isolation, process characterization, process safety, and technology transfer.
- Experience leading project teams delivering active pharmaceutical ingredients across multiple modalities.
- Ability to lead teams ethically, collaboratively, effectively, and cross-functionally.
- Excellent communication, interpersonal, problem-solving, and scientific leadership skills.
Nice to have
- Experience working with external partners and representing an organization in external-facing settings.
- Familiarity with regulatory requirements and CMC activities related to drug development.
Culture & Benefits
- Collaborative environment grounded in scientific rigor, data-driven decision-making, inclusion, integrity, and accountability.
- Medical, dental, vision, life, short-term disability, and long-term disability insurance.
- Paid vacation, company holidays, end-of-year shutdown time, sick time, and paid parental leave.
- 401(k) program with company matching, employee stock purchase plan, and short- and long-term incentive opportunities.
- Fitness and wellness programs, tuition reimbursement of up to $10,000 per year, and employee resource groups.
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