Principal Scientist (ELISA/LC-MS/MS)

Location: Merthyr Tydfil, United Kingdom

Company

hirify.global is a full-service contract research organisation providing clinical development solutions for small and mid-size drug developers, with expertise in clinical pharmacology, oncology, rare diseases, and laboratory services.

What you will do

• Lead regulated bioanalytical studies from client onboarding through final reporting, maintaining scientific integrity and regulatory compliance.
• Develop, optimise, validate, transfer, and apply ELISA and LC-MS/MS analytical methods.
• Provide technical oversight for immunoassay and mass spectrometry platforms, including troubleshooting, instrument performance, and data interpretation.
• Review and approve protocols, SOPs, validation and study reports, CAPAs, file notes, and other regulatory documentation.
• Manage study resources, timelines, quality, costs, documentation, and archiving requirements.
• Mentor scientific staff, support business development, and represent Laboratory Services with clients, auditors, conferences, and external stakeholders.

Requirements

• Degree or equivalent experience in a relevant scientific discipline; an advanced qualification is desirable.
• Extensive experience with ELISA and/or LC-MS/MS in a regulated laboratory environment such as GCP/GCLP, GLP, or GMP.
• Proven experience leading bioanalytical studies involving method development, optimisation, validation, transfer, and routine sample analysis.
• Strong knowledge of bioanalytical validation principles, assay performance, regulatory expectations, data integrity, and GxP compliance.
• Experience reviewing analytical data, validation reports, study documentation, protocols, SOPs, and regulatory guidelines.
• Ability to lead scientific projects, manage priorities, communicate with stakeholders, and mentor scientific staff.

Nice to have

• MSc or PhD in a relevant scientific discipline.
• Experience in a CRO or clinical trial environment and practical experience across both ELISA and LC-MS/MS.
• Knowledge of MHRA Phase I Accreditation scheme requirements.
• Project management or Lean/Six Sigma certification.
• Experience with regulatory audits, client inspections, business development, technical proposals, or scientific team leadership.

Culture & Benefits

• Work alongside experts across clinical development, clinical pharmacology, oncology, rare disease, and laboratory services.
• Exposure to innovative drug development programmes addressing serious unmet medical needs.
• Opportunity to contribute to continuous improvement and the growth of Laboratory Services capabilities.