Member of Technical Staff: Computational Biology

Location: San Francisco, United States

Company

hirify.global is an AI research lab building general biological intelligence, including generative genomics and multimodal genome language models.

What you will do

• Curate and integrate large biological datasets with provenance, quality control, and documented assumptions.
• Build reproducible bioinformatics and analysis pipelines across sequencing, functional genomics, single-cell, perturbational screening, protein, or other relevant data.
• Design data mixtures and sampling strategies for model training and investigate dataset composition, assay effects, duplication, and biological coverage.
• Define biologically meaningful tasks, endpoints, and baselines with modeling and evaluation teams.
• Investigate model predictions and failure modes using available biological evidence.
• Collaborate with wet-lab partners to formulate hypotheses, prioritize validation experiments, and generate training datasets.

Requirements

• Exceptional research record in computational biology, bioinformatics, genomics, or another relevant biology area, demonstrated through a PhD or equivalent research or industry experience.
• Deep expertise in at least one biological domain, with strong scientific judgment and careful attention to data quality and experimental details.
• Strong Python or R programming skills and experience building reliable, reproducible scientific analyses or software.
• Ability to work across biology, machine learning, and engineering, and clearly communicate assumptions, results, and limitations.
• Experience working with agentic coding tools.
• Must be authorized to work in the United States; employment authorization is verified through E-Verify.

Nice to have

• Experience with large-scale biological data curation, data mixing, or bioinformatics infrastructure.
• Experience with biological foundation models or research contributions, datasets, methods, or software used by other scientists.

Culture & Benefits

• Full-time role within the Technical Staff department.
• Equal employment opportunity practices apply across protected characteristics.
• Work focuses on developing both the capabilities of biological design and responsible defenses against engineered threats.