Sr. CMC Project Manager

Location: Remote, United States

Salary: $135,000–$150,000 annually

Company

hirify.global is a clinical-stage, AI-enabled biotech developing medicines and has raised $311M in Series E funding.

What you will do

• Lead program- and portfolio-level CMC planning and execution for multiple small-molecule assets from initial tox supplies through Phase 2 scale-up across drug substance and drug product.
• Own CMC project plans, risk registers, development strategies, timelines, deliverables, and budget tracking.
• Coordinate CROs and CDMOs across China, the EU, and the US, including manufacturing campaigns, batch execution timelines, documentation, issue escalation, and closure.
• Chair cross-functional and CDMO meetings, track actions and decisions, and communicate project status, risks, and mitigation strategies.
• Manage proposals, purchase orders, change orders, multi-year budget forecasts, commitments, accruals, and variance analysis.
• Improve controlled document review workflows and identify opportunities to accelerate timelines, streamline execution, and anticipate resourcing needs.

Requirements

• B.S., M.S., or Ph.D. in Chemistry, Chemical Engineering, Pharmaceutical Sciences, or a similar field; M.S. or Ph.D. preferred.
• 5+ years of CMC project management experience in biotech or pharma, including hands-on small-molecule drug substance and drug product development from IND-enabling through early clinical phases.
• Familiarity with analytical method development, process chemistry, formulation, and regulatory documentation.
• Experience managing external CROs and CDMOs across multiple geographies, including planning, communication, deliverable quality, and issue escalation and closure.
• Ability to lead cross-functional initiatives, set priorities, and manage timelines and budgets in a resource-constrained, fast-paced environment.
• Experience designing and operating structured document workflows, approval processes, and standards in a GxP and submission-relevant context.
• Experience or strong interest in applying AI and automation to operational workflows with safety, transparency, and human oversight.
• Strong technical and operational aptitude with Smartsheet, Box, Domo, Slack, and Zoom, plus comfort building or owning custom applications and integrations.
• Excellent oral and written communication, organizational, interpersonal, problem-solving, flexibility, adaptability, and resourcefulness skills.

Nice to have

• PMP certification.
• Late-stage development experience.

Culture & Benefits

• Remote, full-time role in a fast-paced startup environment.
• Medical, dental, and vision coverage at 90% starting Day 1.
• 401(k) with company match, flexible PTO, and a company-wide weeklong recharge break.
• Adoption assistance.
• Values include Curiosity, Agency, Journey, Charity, and Unity.

Hiring process

• Recruiter screen followed by a hiring manager conversation.
• Work sample, technical interview, and culture interview.
• Applicants will communicate with real hirify.global team members through video or in-person conversations; official communication comes from an @hirify.global.com or @hirify.globalbio.com address.