Director of Chemistry, Small Molecule Process Development and Manufacturing (Biotech)

Location: Cambridge, Massachusetts, United States

Base salary: $188,000–$258,500 per year

Company

hirify.global is a mid-sized biotechnology company developing life-changing medicines across multiple drug modalities.

What you will do

• Lead scientific and engineering teams in designing and executing experiments to optimize, characterize, and improve the robustness and productivity of small-molecule manufacturing processes.
• Guide project teams from early-phase development through late-phase development, including implementation of safe and efficient chemical processes for drug candidates.
• Manage scientific colleagues and mentor future scientific and engineering leaders.
• Develop process knowledge for transferring chemical and biochemical processes from laboratory scale to manufacturing partners.
• Collaborate with Process Engineering, Analytical Chemistry, Oligo Synthesis, Solid Form, and Separations teams on process controls, clinical material supply, and regulatory filings.
• Communicate research results through reports, team discussions, and CMC sections of INDs; engage with CROs and represent hirify.global at consortia and conferences.

Requirements

• M.S. or PhD with 12+ years of relevant experience, including people management, in pharmaceutical or biotechnology settings.
• Strong knowledge of pharmaceutical process chemistry and engineering, including synthetic strategies, impurity controls, analytical methods, purification, isolation, process characterization, process safety, and technology transfer protocols.
• Experience delivering non-clinical and clinical APIs and developing phase-appropriate knowledge packages for CMC support.
• Demonstrated experience leading project teams delivering APIs across several modalities.
• Ability to lead teams ethically, collaboratively, effectively, and cross-functionally.
• Excellent communication and interpersonal skills, with the ability to work in a highly collaborative environment.

Nice to have

• Experience engaging with external partners and representing an organization in external-facing settings.
• Familiarity with regulatory requirements and CMC activities related to drug development.

Culture & Benefits

• Collaborative environment centered on urgency, accountability, inclusion, integrity, first-principles science, and data-driven decision-making.
• Regular employment with short- and long-term incentives, including cash bonuses and equity opportunities.
• Medical, dental, vision, life, disability, fitness, wellness, and employee assistance benefits.
• At least 15 vacation days, end-of-year shutdown time, paid holidays, personal-significance days, sick time, and paid maternity and parental leave.
• 401(k) with company matching, employee stock purchase plan, tuition reimbursement of up to $10,000 annually, and Employee Resource Groups.