Senior Scientist, Discovery Oncology

Location: Boston, Massachusetts, United States; onsite at the Boston laboratory. Domestic relocation may be available. Travel requirements: 10%.

Salary: $119,100–$187,500 annual base salary, plus potential annual bonus and long-term incentive.

Company

hirify.global is a pharmaceutical and healthcare company developing oncology therapeutics and related scientific programs.

What you will do

• Generate actionable biological hypotheses from clinical observations, real-world evidence, patient molecular datasets, and high-resolution technologies.
• Develop experimental models that recapitulate clinical observations using in vitro, ex vivo, and in vivo systems.
• Investigate mechanisms of action, therapeutic response, and resistance across oncology programs.
• Prioritize molecular pathways and therapeutic vulnerabilities to inform biomarker and therapeutic strategies.
• Design, execute, analyze, and interpret laboratory studies and complex biological and molecular datasets.
• Collaborate with translational, computational, and discovery scientists and communicate findings to project teams and stakeholders.

Requirements

• Ph.D. in Cancer Biology, Immunology, Molecular Biology, Biochemistry, Oncology, or a related STEM field; alternatively, an M.S. with 4+ years or a B.S. with 7+ years of relevant industry or academic experience.
• Strong understanding of cancer biology, tumor evolution, and the tumor microenvironment.
• Ability to translate clinical observations into testable biological hypotheses and experimental strategies addressing therapeutic response and resistance.
• Hands-on experience with in vitro and ex vivo systems and molecular biology techniques, including gene perturbation, gene overexpression, cell line engineering, RT-PCR, protein characterization, multi-color flow cytometry, and functional assays.
• Experience with antibody-drug conjugates, bispecific antibodies, and/or small molecules.
• Familiarity with patient-derived models, xenograft models, and translational biomarker approaches.
• Experience using public functional genomics and pharmacology resources such as DepMap, PRISM, TCGA, or related datasets.
• Scientific productivity demonstrated through publications, presentations, or patents, plus strong organizational, communication, presentation, and collaboration skills.
• Ability to work effectively in a fast-paced, matrixed research environment while managing multiple priorities.

Culture & Benefits

• Collaborative, multidisciplinary, and inclusive research environment.
• Regular employee status with medical, dental, vision, insurance, retirement benefits including 401(k), paid holidays, vacation, compassionate leave, and sick days.
• Flexible work arrangements are not applicable; the role is based at the Boston laboratory.
• Visa sponsorship is not available.
• Standard laboratory reagents are used; no valid driving license is required.