Scientist, Analytical Development (mRNA)

Location: Norwood, Massachusetts, United States. This role is 100% onsite. Only U.S. persons—citizens, permanent residents, asylees, or refugees—are eligible because of U.S. export control requirements.

Salary: $109,200–$174,600 per year, plus potential discretionary bonus, incentive compensation, or equity award.

Company

hirify.global develops an mRNA technology platform, vaccines, therapeutics, and other medicines.

What you will do

• Design, develop, optimize, and execute analytical methods for drug substance, drug product, and process intermediates across early development, clinical, and commercial programs.
• Develop electrophoretic, microfluidic, automated separation, biomolecule-analysis, and immuno-based methods, including capillary electrophoresis, CE-SDS, cIEF/icIEF, microchip electrophoresis, automated gel methods, and capillary-based immunoassays.
• Translate product knowledge, critical quality attributes, process-development questions, and control-strategy needs into phase-appropriate analytical requirements and intended use.
• Apply risk-based development, analytical target profile thinking, Design of Experiments, ICH Q14/Q2(R2), and systematic method-performance evaluation.
• Troubleshoot complex analytical challenges, evaluate emerging technologies, and establish standardized platform methods that improve robustness, throughput, automation, scalability, and deployment.
• Author and review procedures, development reports, assessments, regulatory documentation, and support qualification, validation, technical transfer, implementation, and lifecycle management with cross-functional CMC, QC, manufacturing, digital, and quantitative-science partners.

Requirements

• Ph.D. in Analytical Chemistry, Biochemistry, Molecular Biology, Biotechnology, Pharmaceutical Sciences, Bioengineering, Chemical Engineering, or a related field with 0–2 years of relevant experience; or M.S. with 8+ years; or B.S./B.A. with 10+ years of relevant industry experience.
• Strong hands-on analytical method-development experience is required, including at least one relevant platform such as molecular assays, electrophoretic or microfluidic methods, immuno-based assays, or related analytical technologies.
• Ability to plan and execute method-development experiments, interpret complex data, troubleshoot technical problems, and make data-driven recommendations.
• Ability to collaborate across Analytical Development, Process Development, Analytical Sciences, APL, AS&T, QC, QA, Regulatory Affairs, Digital, Automation, and other multidisciplinary teams.
• Ability to maintain scientific rigor, data integrity, laboratory safety, and high-quality documentation.

Nice to have

• Experience with capillary electrophoresis, CE-SDS, cIEF/icIEF, microchip electrophoresis, automated gel electrophoresis, LabChip-type platforms, or related technologies.
• Experience with automated protein or immuno-based platforms, ligand-binding assays, or quantitative biomolecular-analysis methods.
• Experience with mRNA, RNA, plasmid DNA, lipid nanoparticles, vaccines, biologics, gene therapy, or other advanced therapeutic modalities.
• Knowledge of analytical procedure lifecycle principles, including robustness assessment, qualification, validation, technical transfer, continued performance monitoring, and continuous improvement.
• Experience with platform methods, standardized analytical approaches, emerging technologies, proof-of-concept studies, method modernization, or legacy-workflow replacement.
• Experience with laboratory automation, liquid handling, high-throughput workflows, automated sample preparation, LIMS, sample tracking, or reproducible data processing.

Culture & Benefits

• 100% onsite work supporting hands-on collaboration, mentorship, and site-based operations.
• In-person culture centered on platform thinking and digitizing work through code.
• Healthcare and voluntary benefits, fitness, mindfulness, and mental-health support.
• Family planning benefits, including fertility, adoption, and surrogacy support.
• Paid vacation, volunteer days, sabbatical, global recharge days, and discretionary year-end shutdown, plus savings and investment programs.
• Smoke-free, alcohol-free, and drug-free workplace with reasonable accommodations available.