Director, Biotherapeutics Discovery (Biologics)

Location: On-site at hirify.global’s West Coast Hub in South San Francisco, California, United States.

Salary: $204,000–$281,000 per year.

Company

hirify.global is a mid-sized biotechnology company discovering, developing, and delivering therapies for serious neurological and immunological diseases.

What you will do

• Lead and develop a high-performing team while advancing biologics technologies and platform innovation aligned with portfolio priorities.
• Support antibody discovery, engineering, optimization, and candidate selection strategies in partnership with the Cambridge, Massachusetts team.
• Evaluate external innovation opportunities and help adopt next-generation biologics capabilities.
• Shape molecular design strategies covering multi-specifics, novel formats, affinity tuning, epitope targeting, and developability assessments.
• Partner with protein engineering, computational design, pharmacology, translational sciences, Immunology, and Neurology teams to initiate discovery campaigns and guide modality and candidate selection.
• Coach and mentor scientists while building an inclusive culture of innovation, accountability, collaboration, and continuous learning.

Requirements

• Ph.D. in biochemistry, immunology, molecular biology, or a related scientific discipline.
• 12+ years of industry experience in biologics drug discovery, including leadership of antibody discovery and optimization programs.
• Proven success advancing molecules from discovery through candidate nomination.
• Deep expertise in antibody engineering, molecular design, and biologics discovery workflows.
• Experience across biologics modalities, including bispecifics, fusion proteins, and conjugates.
• Demonstrated experience leading and developing scientific teams.
• Strong cross-functional partnership experience, including collaboration with disease biology teams.
• Excellent communication and leadership skills, with the ability to influence scientific direction across teams and sites.

Nice to have

• Experience in translational immunology and a strong understanding of immunology disease biology.
• Experience partnering with Immunology or Neurology research teams.
• Background in early target assessment and discovery campaign initiation.
• Experience identifying and sourcing external innovation through collaborations with CROs, biotech companies, or academic groups.
• Familiarity with computational design or AI/ML applications in biologics discovery.

Culture & Benefits

• On-campus work environment with collaboration across research sites.
• Medical, dental, vision, life, short-term and long-term disability insurance.
• Paid vacation, year-end shutdown time, company holidays, personal significance days, sick time, and paid maternity and parental leave.
• Short- and long-term incentives, cash bonus opportunities, equity incentives, 401(k) matching, and an employee stock purchase plan.
• Fitness and wellness programs, tuition reimbursement up to $10,000 per calendar year, and Employee Resource Group participation.
• Commitment to inclusion, belonging, scientific excellence, learning, and career growth.