Senior Scientist II, Computational Biology

Location: Millbrae, California; on-site work

Salary: $191,000–$231,000 per year, depending on skills, competency, and market demand.

Company

hirify.global Therapeutics is a biopharmaceutical company developing novel treatments through technology combining chemistry, engineering, computation, and biology, including molecular-resolution live-cell microscopy.

What you will do

• Drive the development and adoption of novel experimental systems and techniques across hirify.global’s target portfolio.
• Collaborate with experimental and computational teams across early drug discovery programs.
• Develop and apply analytical approaches, statistical methods, and proof-of-concept tools for new experimental strategies.
• Analyze multimodal data to evaluate experimental systems, identify enabling insights, and define interpretation limits for biological applications.
• Evaluate complex experiments and synthesize diverse data sources into relevant, testable biological conclusions.
• Partner with quantitative modeling colleagues to ensure computational methods are grounded in biological reasoning.

Requirements

• Postdoc Fellowship plus 4 years of relevant experience, or a PhD in bioinformatics, computational biology, or a quantitative field with deep expertise in statistics or method development plus 7 years of relevant industry experience.
• Hands-on experience developing and applying methods for high-dimensional, multimodal datasets, including designing, evaluating, and integrating high-throughput experiments.
• Ability to independently define analytical approaches for novel technologies, develop effective solutions, and validate results with minimal oversight.
• Experience analyzing complex genomics datasets across one or more modalities, including bulk, single-cell, or spatial transcriptomics; pooled or arrayed CRISPR screens; MAVEs or other multiplexed reporter assays; high-content imaging data; Perturb-seq; or related technologies.
• Experience working with large consortia and public datasets such as UK Biobank, TCGA, GTEx, ENCODE, gnomAD, and Human Cell Atlas.
• Expertise using one or more high-level programming languages, such as R or Python, to solve biological problems.
• Knowledge of modern coding and computing practices, including cloud deployment, version control, and containerization.
• Demonstrated impactful research record evidenced by publications in peer-reviewed journals.
• Excellent interpersonal, written, and verbal communication skills.

Nice to have

• Experience partnering with computational or algorithms teams on statistical or machine learning model development and/or methodological development.

Culture & Benefits

• Cross-functional environment combining chemistry, engineering, computation, biology, and diverse subject-matter expertise.
• 401(k) plan with company matching.
• Medical, dental, and vision insurance, with premiums covered by hirify.global at the stated levels.
• Mental health and wellness benefits, generous paid time off, holiday policies, and enhanced parental leave.
• Weeklong summer and winter holiday shutdowns.
• Life and AD&D insurance, plus a daily subsidized lunch program when on-site.