Distinguished Scientist, Translational Clinical Biomarkers (Oncology)

Location: Hybrid; primary location in Rahway, New Jersey, with additional locations in Pennsylvania and Boston. The role is available to US, Canada, and Puerto Rico residents, with domestic relocation and 25% travel required.

Salary: $255,800–$402,700 annually for the primary location, plus potential annual bonus and long-term incentive.

Company

hirify.global develops medicines and conducts biomedical research, including oncology therapeutics, clinical development, biomarkers, diagnostics, and translational science.

What you will do

• Lead a Biomarker Center of Excellence and supervise PhD- and MD-level scientists embedded in oncology clinical development programs.
• Develop, align, and execute end-to-end biomarker and translational strategies across oncology therapeutic platforms from pre-FIH through Phase 3 and beyond.
• Build testable hypotheses and protocol-specific biomarker plans with clinical development, discovery, diagnostics, informatics, biostatistics, molecular assay, and clinical trial teams.
• Develop statistical analysis plans, analysis reports, and data communication plans; participate in clinical data analysis and interpretation.
• Identify scientific and technical advances, novel technologies, implementation risks, and mitigation plans for clinical biomarker analysis.
• Engage external key opinion leaders, support publications, health authority engagements, registrational efforts, post-marketing commitments, and due diligence activities.

Requirements

• Ph.D., M.D., or M.D./Ph.D. with at least 15 years of experience in oncology biomarker studies and translational clinical research.
• Extensive experience in clinical trial development and execution, including translational needs in clinical studies and experimental and bioinformatic aspects of biomarker development.
• Strong leadership skills and a proven record of collaboration in cross-functional, highly matrixed drug discovery or clinical development groups.
• Proven achievement in biomedical research and scientific scholarship.
• In-depth understanding of end-to-end drug, biomarker, and diagnostic development, including biomarker discovery, diagnostic development, and early or late drug development.
• Strong scientific expertise in translational biomarkers for antibody-drug conjugates and T-cell engagers, with deep knowledge of cancer biology, cancer immunology, and clinical oncology.
• Strong communication and analytical skills for working with senior leadership, clinicians, scientists, and broad stakeholders.
• Experience directly managing PhD- and MD-level scientists, including demonstrated talent development.

Nice to have

• Experience communicating with health authorities and working with EU IVDR, China HGRAC, Japan PMDA, and other global markets for biomarkers and translational analyses.
• Prior experience in oncology drug discovery.

Culture & Benefits

• Hybrid work arrangement with a regular day shift.
• Medical, dental, vision, and other insurance benefits for employees and families.
• Retirement benefits including a 401(k).
• Paid holidays, vacation, compassionate leave, and sick days.
• Inclusive environment that values diverse perspectives, respectful challenge, and collective problem-solving.