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9 дней назад

Postdoctoral Research Fellow - Sethi Lab (Cancer Biology)

72 000 - 76 385$
Формат работы
onsite
Тип работы
fulltime
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

Текст:
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TL;DR
Postdoctoral Research Fellow - Sethi Lab (Cancer Biology): Investigating molecular mechanisms controlling cancer cell-state transitions through experimental studies of chromatin regulation, metabolism, differentiation, and tumor plasticity with an accent on mechanistic biology and translational oncology. Focus on designing independent experiments, validating mechanisms in organoids and cancer models, and developing therapeutic strategies to control drug-resistant cell states.

Location: Boston, MA, US; 100% onsite

Salary: $72,000–$76,385 per year

Company

hirify.global conducts cancer research and patient care in collaboration with Harvard Medical School and the Broad Institute.

What you will do

  • Design and execute independent experiments investigating molecular mechanisms that control cancer cell-state transitions.
  • Analyze and interpret experimental data and develop mechanistic hypotheses.
  • Study chromatin regulation, retinoid metabolism, differentiation, and cancer-cell plasticity.
  • Validate mechanisms using patient-derived organoids, human specimens, genetically engineered mouse models, xenografts, and other physiologically relevant systems.
  • Collaborate with computational and translational scientists and prepare manuscripts and scientific presentations.
  • Contribute to grant development and mentor junior laboratory members.

Requirements

  • Ph.D., M.D., or M.D./Ph.D.
  • Strong training in experimental biology.
  • Demonstrated creativity, scientific judgment, and ability to work independently.
  • Intellectual ambition, scientific rigor, and the ability to learn quickly.

Nice to have

  • Experience in molecular biology and protein biochemistry, transcription factor biology, chromatin remodeling or epigenetics, protein–protein interactions, cell signaling and cancer biology, CRISPR-based genetic engineering, organoid or stem cell biology, quantitative cell biology or microscopy, in vivo studies, or synthetic biology.
  • Experience with mouse models.

Culture & Benefits

  • Six to eighteen months of overlap with experienced senior investigators for technical knowledge transfer and project continuity.
  • Access to established mechanistic groundwork, model systems, reagents, and preliminary observations.
  • Scientific collaboration across hirify.global, Harvard Medical School, and the Broad Institute.
  • Inclusive, diverse, and equitable working environment.
  • Applications are reviewed on a rolling basis, and the start date is flexible.

Hiring process

  • Submit a CV, a brief cover letter of no more than two pages, and contact information for three references, including the Ph.D. advisor.
  • Applications are reviewed on a rolling basis.

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