10 дней назад
Associate Scientist/ Scientist (Influenza Virology)
86 320 - 154 960$
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Associate Scientist/ Scientist (Influenza Virology): Building and leading the wet-lab program for influenza A virus research, including cell culture, virus generation, molecular biology, and advanced cellular model systems with an accent on laboratory setup, virology operations, and in-cell structural biology. Focus on developing recombinant and CRISPR-engineered systems, managing BSL-2 workflows, and establishing research infrastructure while mentoring scientific staff.
Location: Memphis, Tennessee, United States; onsite laboratory role
Salary: $86,320–$154,960 per year for the Scientist level; $65,520–$114,400 per year for the Associate Scientist level
Company
conducts biomedical research focused on improving treatment and outcomes for children.
What you will do
- Lead the laboratory's mammalian cell culture and influenza virology operations.
- Maintain cell lines and primary cultures, produce and validate influenza virus stocks, and generate recombinant and tagged viruses using reverse genetics.
- Develop stable and CRISPR-engineered cell lines and perform cloning, transfections, immunoprecipitations, western blotting, fluorescence microscopy, and confocal imaging.
- Establish laboratory infrastructure, procure and commission equipment, manage inventories, and oversee service and maintenance activities.
- Develop SOPs, biosafety documentation, electronic notebooks, protocol repositories, and data management systems for BSL-2 laboratory operations.
- Train, mentor, and supervise junior staff and trainees while contributing to publications, grants, presentations, and scientific conferences.
Requirements
- Bachelor's degree in cell biology, virology, biochemistry, molecular biology, or a related scientific field.
- Relevant research experience: 8 years for Scientist, or 7+ years for Associate Scientist; reduced experience requirements apply with a master's or doctoral degree.
- Experience with mammalian and primary cell culture, influenza propagation and infection, plaque or TCID50 assays, viral stock quality control, and BSL-2 biosafety practices.
- Experience with molecular biology, CRISPR-based genome engineering, stable cell line generation, protein biochemistry, fluorescence microscopy, and confocal imaging.
- Strong laboratory documentation, inventory management, regulatory compliance, communication, organization, and scientific leadership skills.
- Work must be performed onsite in Memphis, Tennessee.
Nice to have
- Influenza reverse genetics and recombinant virus generation.
- Organoid, air-liquid interface, or other tissue-derived model systems.
- Electronic laboratory notebook or laboratory information management system administration.
- Electron microscopy or mass spectrometry sample preparation, proteomics, or crosslinking mass spectrometry.
- Experience establishing laboratories and mentoring scientific staff or students.
Culture & Benefits
- Opportunity to build a new laboratory from its inception with significant autonomy and visibility.
- Approximately equal emphasis on laboratory leadership and independent research.
- Access to cryo-EM/ET, Titan Krios, Plasma-FIB, Aquilos, and other advanced research infrastructure.
- Opportunities for first-author publications and collaboration with influenza, structural biology, and computational biology researchers.
- High-containment and animal studies are conducted through collaborations with the St. Jude Center of Excellence for Influenza Research and Response.
Hiring process
- The final level, Associate Scientist or Scientist, is determined by qualifications, experience, and assessment during hiring.
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