5 дней назад
Research Associate (Biomaterials)
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Research Associate (Biomaterials): Developing methacrylated hyaluronic acid hydrogel systems for controlled stiffening and softening during live-cell imaging, with an accent on mechanobiology, integrin-mediated cell–matrix interactions, and biomaterial validation. Focus on establishing reproducible hydrogel workflows, analysing receptor-mediated signalling with advanced imaging and biochemical methods, and leading research outputs and funding applications.
Location: Oxford Road, Manchester, United Kingdom. Applicants must demonstrate the right to work in the UK. This role is not eligible for Skilled Worker visa sponsorship.
Company
is a university supporting research and education.
What you will do
- Develop and optimise methacrylated hyaluronic acid hydrogel systems for controlled stiffening and softening during live-cell imaging.
- Characterise hydrogel properties, reproducibility, and compatibility with mammalian cell culture.
- Investigate integrin-dependent mechanobiology at cell–matrix adhesions and prepare findings for publication.
- Establish hydrogel fabrication and quality-control workflows, including practical training and technical support for laboratory members.
- Lead research outputs and develop external research funding applications with colleagues across relevant disciplines.
Requirements
- PhD in materials science, biomaterials, bioengineering, cell biology, or a closely related discipline, with substantial postdoctoral or equivalent research experience.
- Extensive independent experience developing and troubleshooting multiple biomaterial platforms for biological research, including patient-derived cancer-cell models.
- Established research track record in mechanobiology and receptor-mediated mechanotransduction involving GPCR/G-protein, integrin, or related cell-surface signalling systems.
- Experience with complementary biochemical, cellular, and imaging methods, including protein functionalisation, immunoblotting, immunocytochemistry, co-immunoprecipitation, small-GTPase activity assays, cellular fractionation, super-resolution microscopy, and transcriptomic datasets.
- Research independence and leadership appropriate to a senior postdoctoral researcher, including leading publications and developing grant or fellowship applications.
- Applicants must have the right to work in the UK; Skilled Worker visa sponsorship is not available.
Nice to have
- Experience with hyaluronic acid-based, methacrylated, or photocrosslinkable hydrogels and light-mediated biomaterial fabrication.
- Quantitative live-cell imaging, microfluidics, and analysis of mechanically regulated cell behaviour.
- Biomaterial characterisation using rheology, atomic force microscopy, or mechanical testing.
- Experience measuring integrin activation, focal-adhesion signalling, or related cell–matrix adhesion processes.
Culture & Benefits
- Inclusive environment that values diverse perspectives, transferable skills, and real-world experience.
- Generous employer pension contribution.
- 29 days of annual leave plus bank holidays and Christmas closure.
- Ride-to-work and electric vehicle car schemes.
- Flexible and hybrid working options are available according to role requirements.
Будьте осторожны: если работодатель просит войти в их систему, используя iCloud/Google, прислать код/пароль, запустить код/ПО, не делайте этого - это мошенники. Обязательно жмите "Пожаловаться" или пишите в поддержку. Подробнее в гайде →
Похожие вакансии
6 дней назад
Associate Research Leader (Stem Cell Biology)
6 дней назад
Scientist I – Material-Biomimetic Membrane Scientist
25 400 - 38 200GBP
10 дней назад
Technical Specialist, Large Molecule Bioanalysis
11 дней назад
Scientist, Clinical Biomarker Laboratory, Immuno-Assays - Cell Based (Immunoassays)
6 дней назад
Scientist, Genetic Assays (mRNA)
10 дней назад