7 дней назад
Senior Scientist - Structural Biology (m/f/d) (X-ray Crystallography)
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Senior Scientist - Structural Biology (m/f/d) (X-ray Crystallography): Planning and delivering structural biology projects for early-stage drug discovery, including crystallization experiments, X-ray data processing, and protein-ligand structure determination with an accent on structure-based drug design and client-facing scientific communication. Focus on designing crystallization and data collection workflows, solving complex protein structures, and evaluating results with specialist software on Linux.
Location: On-site in Munich, Germany
Company
's Structural Biology group supports early-stage drug discovery projects in collaboration with Crelux and client teams.
What you will do
- Plan and run structural biology client projects focused on structure-based drug design.
- Plan crystallization and data collection experiments for a broad range of target classes.
- Process X-ray crystallography data and determine protein-ligand crystal structures.
- Communicate structural biology results to internal, external, and interdisciplinary project teams.
- Document and evaluate scientific protocols and results while meeting project timelines.
- Maintain current knowledge of advances in structural biology.
Requirements
- PhD in biology, biochemistry, chemistry, or a related subject.
- Practical and theoretical knowledge of construct design, crystallization, and structure determination.
- Experience with Global Phasing, CCP4, XDS, PyMOL, and ChimeraX running on Linux.
- Strong planning, documentation, interpersonal, and interdisciplinary communication skills.
- Fluent spoken and written English required; German is ideally desirable.
Nice to have
- Experience with cryo-electron microscopy, crystallographic fragment screening, or protein design.
- Programming experience with Bash and Python.
- Experience with SQL/MariaDB databases or Linux system administration.
Culture & Benefits
- Collaboration with various departments and interdisciplinary project teams.
- Work on early-stage drug discovery projects covering a wide range of target classes.
- Client-facing scientific communication within structural biology projects.
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