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7 дней назад

Senior Scientist - Structural Biology (m/f/d) (X-ray Crystallography)

Формат работы
onsite
Тип работы
fulltime
Грейд
senior
Английский
c1
Страна
Germany
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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TL;DR
Senior Scientist - Structural Biology (m/f/d) (X-ray Crystallography): Planning and delivering structural biology projects for early-stage drug discovery, including crystallization experiments, X-ray data processing, and protein-ligand structure determination with an accent on structure-based drug design and client-facing scientific communication. Focus on designing crystallization and data collection workflows, solving complex protein structures, and evaluating results with specialist software on Linux.

Location: On-site in Munich, Germany

Company

hirify.global's Structural Biology group supports early-stage drug discovery projects in collaboration with Crelux and client teams.

What you will do

  • Plan and run structural biology client projects focused on structure-based drug design.
  • Plan crystallization and data collection experiments for a broad range of target classes.
  • Process X-ray crystallography data and determine protein-ligand crystal structures.
  • Communicate structural biology results to internal, external, and interdisciplinary project teams.
  • Document and evaluate scientific protocols and results while meeting project timelines.
  • Maintain current knowledge of advances in structural biology.

Requirements

  • PhD in biology, biochemistry, chemistry, or a related subject.
  • Practical and theoretical knowledge of construct design, crystallization, and structure determination.
  • Experience with Global Phasing, CCP4, XDS, PyMOL, and ChimeraX running on Linux.
  • Strong planning, documentation, interpersonal, and interdisciplinary communication skills.
  • Fluent spoken and written English required; German is ideally desirable.

Nice to have

  • Experience with cryo-electron microscopy, crystallographic fragment screening, or protein design.
  • Programming experience with Bash and Python.
  • Experience with SQL/MariaDB databases or Linux system administration.

Culture & Benefits

  • Collaboration with various departments and interdisciplinary project teams.
  • Work on early-stage drug discovery projects covering a wide range of target classes.
  • Client-facing scientific communication within structural biology projects.

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