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5 дней назад

Project Chemist (Mass Spectrometry)

Формат работы
onsite
Тип работы
fulltime
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

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TL;DR
Project Chemist (Mass Spectrometry) (LC-MS/MS and HPLC): Performing routine LC-MS/MS assays, sample preparation, instrument operation, troubleshooting, and analytical data review in a GMP laboratory with an accent on peptide mapping, intact mass analysis, and protein and small-molecule quantitation. Focus on maintaining instrument performance, validating analytical methods, documenting compliant results, and resolving unexpected test outcomes.

Location: Houston, Texas, United States

Company

hirify.global provides FDA-registered cGMP testing, calibration, sterility, microbial detection, beyond-use dating, and active ingredient potency services for pharmaceutical, healthcare, and compounding-industry clients.

What you will do

  • Perform routine LC-MS/MS assays, including peptide mapping, intact mass analysis, and protein or small-molecule quantitation.
  • Prepare samples, standards, mobile phases, buffers, and other laboratory solutions.
  • Operate, maintain, calibrate, and monitor LC-MS/MS, HPLC, and UHPLC systems according to SOPs.
  • Review, interpret, organize, and document analytical data and laboratory records.
  • Perform system suitability and QC checks, identify unexpected results, and troubleshoot basic instrument or method issues.
  • Support method optimization, validation activities, laboratory organization, and cross-functional project delivery.

Requirements

  • Bachelor’s or Master’s degree in Chemistry, Analytical Chemistry, Biochemistry, or a related field.
  • Hands-on experience with LC-MS/MS instrumentation and workflows, as well as HPLC or UHPLC systems.
  • Experience with protein and peptide characterization, sample preparation, data analysis, and biological or chemical sample matrices.
  • Familiarity with GMP and applicable regulatory requirements, including FDA and ICH guidance.
  • Strong attention to detail, documentation, organization, communication, and independent working skills.
  • Ability to work collaboratively and use laboratory software and data management systems.

Nice to have

  • Experience with LC-MS/MS quantitation using MRM or SIR acquisition modes.
  • Knowledge of peptide synthesis, purification techniques, protein chemistry, and post-translational modifications.
  • Experience in a pharmaceutical or biotechnology setting.
  • HPLC certification.

Culture & Benefits

  • Work in a state-of-the-art scientific testing and calibration laboratory.
  • Contribute to quality-focused solutions supporting patient safety and regulatory compliance.
  • Collaborate with cross-functional laboratory and customer-facing teams.
  • Work in an environment emphasizing innovation, detail orientation, ownership, and reliable completion of analytical deliverables.

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