5 дней назад
Project Chemist (Mass Spectrometry)
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Project Chemist (Mass Spectrometry) (LC-MS/MS and HPLC): Performing routine LC-MS/MS assays, sample preparation, instrument operation, troubleshooting, and analytical data review in a GMP laboratory with an accent on peptide mapping, intact mass analysis, and protein and small-molecule quantitation. Focus on maintaining instrument performance, validating analytical methods, documenting compliant results, and resolving unexpected test outcomes.
Location: Houston, Texas, United States
Company
provides FDA-registered cGMP testing, calibration, sterility, microbial detection, beyond-use dating, and active ingredient potency services for pharmaceutical, healthcare, and compounding-industry clients.
What you will do
- Perform routine LC-MS/MS assays, including peptide mapping, intact mass analysis, and protein or small-molecule quantitation.
- Prepare samples, standards, mobile phases, buffers, and other laboratory solutions.
- Operate, maintain, calibrate, and monitor LC-MS/MS, HPLC, and UHPLC systems according to SOPs.
- Review, interpret, organize, and document analytical data and laboratory records.
- Perform system suitability and QC checks, identify unexpected results, and troubleshoot basic instrument or method issues.
- Support method optimization, validation activities, laboratory organization, and cross-functional project delivery.
Requirements
- Bachelor’s or Master’s degree in Chemistry, Analytical Chemistry, Biochemistry, or a related field.
- Hands-on experience with LC-MS/MS instrumentation and workflows, as well as HPLC or UHPLC systems.
- Experience with protein and peptide characterization, sample preparation, data analysis, and biological or chemical sample matrices.
- Familiarity with GMP and applicable regulatory requirements, including FDA and ICH guidance.
- Strong attention to detail, documentation, organization, communication, and independent working skills.
- Ability to work collaboratively and use laboratory software and data management systems.
Nice to have
- Experience with LC-MS/MS quantitation using MRM or SIR acquisition modes.
- Knowledge of peptide synthesis, purification techniques, protein chemistry, and post-translational modifications.
- Experience in a pharmaceutical or biotechnology setting.
- HPLC certification.
Culture & Benefits
- Work in a state-of-the-art scientific testing and calibration laboratory.
- Contribute to quality-focused solutions supporting patient safety and regulatory compliance.
- Collaborate with cross-functional laboratory and customer-facing teams.
- Work in an environment emphasizing innovation, detail orientation, ownership, and reliable completion of analytical deliverables.
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