Associate Scientist, Downstream Processing (Biotherapeutics)

Location: Malvern, Pennsylvania, United States of America; onsite

Company

Johnson & Johnson develops healthcare, Innovative Medicine, and MedTech solutions, including biotherapeutic treatments and medical technologies.

What you will do

• Develop and apply high-throughput purification strategies for early-phase biotherapeutics, including monoclonal, bispecific, and multispecific antibodies and bioconjugates.
• Execute bench-scale chromatography and filtration experiments focused on product quality attributes, recovery, and manufacturing fit.
• Support process characterization, scale-up, and technology transfer for downstream unit operations.
• Collaborate with upstream, analytical development, formulation sciences, and manufacturing organizations.
• Author and review technical and regulatory documents while maintaining accurate experimental records.
• Follow cGLP, safety, environmental, EHSS, and company documentation requirements.

Requirements

• Bachelor’s degree in Chemical Engineering, Biochemistry, Biotechnology, or a related discipline with 0–5 years of relevant experience, or a master’s degree with 0–3 years of relevant experience.
• Familiarity with protein purification, bioprocessing, or related scientific methods.
• Basic understanding of experimental design, execution, and analysis.
• Strong written and verbal communication, organization, and problem-solving skills.
• Ability to work independently with limited supervision and collaboratively in a team.
• Proficiency in Microsoft Excel, Word, and PowerPoint.

Nice to have

• Understanding of statistical experimental design and DoE methodology.
• Hands-on experience with ÄKTA fast protein liquid chromatography systems.
• Experience with chromatography, depth filtration, tangential flow filtration, UFDF, SDS-PAGE, or UV/Vis methods.
• Experience with JMP, Minitab, or related statistical design software.

Culture & Benefits

• Work within Innovative Medicine on treatments and cures for complex diseases.
• Collaborate across scientific, analytical, formulation, and manufacturing functions.
• Inclusive work environment with equal employment opportunity and applicant accommodation support.