Senior Director of Clinical Operations

Location: Remote in the US

Company

Developing clinical-stage therapeutic assets through integrated, technology-first clinical trial infrastructure, with a focus on improving biopharma development.

What you will do

• Own clinical and regulatory delivery for one in-licensed asset from trial start-up through close-out.
• Ensure trial quality, safety, timeline, and budget performance while working closely with the Clinical Program Manager.
• Identify and mitigate risks and contribute to the asset’s clinical development plan.
• Shape Clinical Operations SOPs, processes, monitoring standards, oversight practices, and quality systems across the portfolio.
• Advise on clinical delivery requirements for Citrus and other trial systems in partnership with Product and technology teams.
• Provide portfolio-wide sign-off on safety, trial design, proportionality, essential documentation, and quality issues while mentoring the ClinOps team.

Requirements

• 15+ years of clinical operations experience with hands-on delivery across multiple Phase 2 drug trials.
• Experience with complex neurology trials in chronic indications, ideally Parkinson’s disease.
• First-hand experience making clinical, quality, and safety decisions across multiple trials.
• Senior review and sign-off experience for monitoring plans, RAMPs, protocol deviations, and eTMF readiness.
• Experience designing SOPs and processes at portfolio or function level and influencing EDC, CTMS, and eTMF systems.
• Experience across multiple regulatory jurisdictions; FDA experience is preferred.

Nice to have

• Experience with FDA-facing clinical trials.
• Experience in Parkinson’s disease trials.

Culture & Benefits

• Mission-driven, high-growth, VC-funded startup environment.
• Competitive salary and meaningful stock options.
• 27 days of annual leave plus 11 national holidays.
• US health insurance through TriNet, enhanced parental leave, and a monthly wellness allowance.
• $2,000 annual learning and development allowance.
• Remote team lunches, virtual and in-person company events, and access to gym and retail discounts.

Hiring process

• Initial 30-minute conversation with a Senior Talent Partner.
• Second interview with the VP Operations and another interviewer, followed by a functional interview with the CMO and Head of Quality.
• Final 30-minute values interview with two team members.