Biostatistics Associate Director (HYBRID)

Location: Boston, MA, United States. Hybrid-eligible with remote work up to two days per week, or on-site five days per week with ad hoc flexibility.

Salary: $174,800–$262,200 per year, plus annual bonus and equity awards.

Company

Vertex is a global biotechnology company focused on scientific innovation and developing better outcomes for patients.

What you will do

• Lead scientific and operational statistical work across multiple clinical trials, observational studies, and real-world data investigations.
• Lead biostatistics projects or major project components, including work allocation, review, and strategic technical contributions.
• Design and implement statistical methods at study and project level, and author Statistical Analysis Plans, TFL shells, xFDR plans, KRMs, and Data Dissemination Plans.
• Collaborate with statistical programming and cross-functional teams to deliver high-quality TFLs and contribute to clinical study reports.
• Provide statistical guidance to internal review boards, regulators, payers, and other external stakeholders.
• Author or co-author methodological publications, study publications, and posters while contributing to advanced departmental initiatives.

Requirements

• Ph.D. in Statistics or Biostatistics, or an equivalent combination of education and experience.
• Typically seven years of experience with a Ph.D. or equivalent experience.
• In-depth competence with SAS and R statistical software.
• In-depth understanding of advanced statistical methods used in drug development.
• Experience with NDA/MAA submissions and direct dealings with US and European regulators.
• Strong critical thinking, logical problem-solving, written communication, verbal communication, and cross-functional collaboration skills.

Nice to have

• Prior staff management experience.
• Experience presenting to peer protocol review committees, statistical review forums, or other senior review boards.

Culture & Benefits

• Continuous learning focused on advances in AI, technology, automation, and industry trends.
• Medical, dental, and vision benefits.
• Generous paid time off, including summer and winter company shutdowns.
• Educational assistance, including student loan repayment programs.
• Commuting subsidy, matching charitable donations, and 401(k).