Clinical Lead Early Development and Experimental Therapeutics - Oncology

Location: Cambridge, MA or Morristown, NJ; hybrid; US and Puerto Rico residents only

Salary: $206,250–$297,916.66 per year

Company

hirify.global is an R&D-driven biopharmaceutical company developing medicines and vaccines through immunoscience, AI, data, and digital platforms.

What you will do

• Design and lead early clinical development studies for oncology assets, from first-in-human studies through phase 2a.
• Develop protocols covering dose escalation, proof-of-mechanism, proof-of-concept, natural history, mechanistic, and signal-seeking studies.
• Provide clinical expertise for preclinical data interpretation, translational medicine, biomarker research, and human target validation.
• Make decisions on protocol design, dose selection, study safety, and early Go/No-Go recommendations.
• Oversee medical monitoring, CROs, clinical operations, study documentation, data review, and clinical study reporting.
• Coordinate global project teams and collaborate with research, toxicology, pharmacology, regulatory, safety, biostatistics, and biomarker specialists.

Requirements

• MD or equivalent required.
• At least 3 years of clinical research experience required.
• English required.
• Experience designing or conducting early clinical trials, ideally phase 1/2a oncology studies.
• Experience with medical safety oversight, translational or biomarker research, and interpretation of preclinical data.
• Knowledge of GCP practices, cross-functional team leadership, clinical documentation, and work in a matrix organization.

Nice to have

• MD and PhD or comparable bench science experience.
• Experience with combination therapies and drugs targeting cytoplasmic signaling pathways.
• Experience using emerging digital or AI-driven tools and working in a global pharmaceutical environment.
• Postgraduate residency training, laboratory research, or late-phase clinical trial experience.

Culture & Benefits

• Work with a future-focused biopharmaceutical research organization addressing unmet needs in oncology.
• Opportunities for career growth through promotions or international and lateral moves.
• Healthcare, prevention, wellness, and family benefits, including at least 14 weeks of gender-neutral parental leave.
• Access to AI, data, and digital platforms supporting drug discovery and development.
• Collaborative work with investigators, clinical experts, regulatory authorities, CROs, and multidisciplinary internal teams.