Senior Director, Biostatistics

Location: South San Francisco, United States; on-site at least three days per week

Salary: $250,000–$300,000 per year

Company

Clinical-stage biotechnology company developing therapies for genetically validated cardioendocrine diseases, including severe hypertriglyceridemia and acromegaly.

What you will do

• Lead statistical planning, analysis, and interpretation across preclinical and clinical development programs.
• Represent biostatistics on clinical study teams and develop strategic statistical approaches aligned with regulatory and industry standards.
• Define and oversee best practices for scientific and clinical data handling, analysis, and interpretation.
• Oversee CROs, biometrics vendors, consultants, statisticians, programmers, and data managers.
• Support global regulatory strategy, submissions, scientific publications, and regulatory interactions.
• Assess biometrics risks, resourcing, infrastructure, and execution, providing updates to cross-functional and leadership teams.

Requirements

• PhD and 10+ years of biostatistics experience in the biotechnology or pharmaceutical industry.
• Expertise in applied statistics, including complex dataset design and analysis, multiple imputation, and longitudinal data analysis.
• Experience leading teams and vendors across statistics, programming, and data management.
• In-depth knowledge of all phases of global drug development and regulatory submission processes.
• Ability to work cross-functionally, manage projects under pressure, and communicate effectively with diverse stakeholders.
• Ability to work on-site in South San Francisco at least three days per week.

Nice to have

• Experience in cardiovascular, metabolic, or rare diseases.
• Experience supporting large, long-term studies and clinical development plans.
• Experience supporting scientific publications and communications strategies.

Culture & Benefits

• Collaborative, hands-on environment with direct contribution expected at every level.
• Opportunity to work with a dynamic team advancing a clinical-stage therapeutic pipeline.
• Role combines strategic leadership with hands-on statistical expertise.