Director, Nonclinical Toxicology Operations

Location: Brisbane, California, United States — onsite. On-site presence is expected to support close partnership with laboratory and program teams.

Salary: $220,700–$252,667

Company

hirify.global is a clinical-stage biopharmaceutical company developing targeted protein degradation medicines for cancer and inflammatory diseases using an AI-integrated discovery engine and ligase expertise.

What you will do

• Plan and coordinate GLP and non-GLP in vivo and in vitro safety studies, including exploratory toxicology, dose-range finding, repeat-dose toxicology, safety pharmacology, and genetic toxicology.
• Identify and manage CROs and specialty vendors, including bid solicitation, vendor selection, contracts, scope changes, budgets, invoices, and forecasting.
• Maintain integrated study timelines, monitor milestones and deliverables, coordinate review cycles, and escalate schedule or safety issues appropriately.
• Manage discovery and development programs from late lead optimization through candidate selection, IND-enabling studies, and IND filing.
• Integrate chemistry, DMPK, pharmacology, toxicology, CMC, and regulatory plans while maintaining dashboards, risk registers, critical paths, and resource views.
• Lead project meetings, governance materials, scenario planning, and continuous improvement of project management processes.

Requirements

• Master’s degree or Ph.D. in toxicology, pharmacology, biology, chemistry, pharmaceutical sciences, or a related life sciences discipline.
• Typically 10+ years of relevant biotech or pharmaceutical experience with ownership of multidisciplinary project management.
• Experience managing CROs and external vendors, including contracting, budget tracking, and performance management.
• Direct experience supporting and coordinating IND-enabling activities, with working knowledge of small-molecule drug discovery, nonclinical safety assessment, and GLP requirements.
• Proficiency with integrated timelines, critical-path analysis, resource planning, and project management tools such as MS Project, Smartsheet, or Planisware.
• On-site presence in Brisbane, California is expected.

Nice to have

• Formal project management credential such as PMP.
• Experience in targeted protein degradation, oncology, or immunology.
• Familiarity with AI tools.

Culture & Benefits

• Collaborative, team-oriented working environment.
• Solutions- and results-oriented approach.
• Hands-on, resourceful culture open to diverse points of view.
• Close collaboration with laboratory and program teams across functions and sites.