Sr. Scientist, Toxicology (Cell And Gene Therapy)

Location: Hybrid role based in Philadelphia, Pennsylvania, or Somerset, New Jersey, United States

Salary: $127,313–$167,099 USD base pay annually, plus performance-based bonus and/or equity for eligible employees.

Company

hirify.global is a biotechnology company developing cell and gene therapies, including CAR-T, TCR-T, and natural killer cell-based therapies for serious diseases.

What you will do

• Support toxicology activities across discovery and development-stage cell and gene therapy programs.
• Design, monitor, interpret, and report nonclinical safety, pharmacology, biodistribution, and pharmacokinetic studies.
• Integrate toxicology and pharmacology data to support candidate selection, risk assessment, and program progression.
• Manage CRO study activities, including protocol review, monitoring, data interpretation, and final report review.
• Collaborate with Pharmacology, CMC, Clinical, Regulatory Affairs, and Program Management teams.
• Prepare briefing packages, pre-IND and IND submissions, investigator brochures, and responses to health authority questions.

Requirements

• Ph.D., DVM, PharmD, or equivalent degree in Toxicology, Pharmacology, Immunology, or a related discipline.
• At least 5 years of experience in nonclinical toxicology or a related field within biotechnology or pharmaceutical R&D.
• Working knowledge of GLP toxicology, nonclinical pharmacology studies, CRO management, and regulatory expectations.
• Understanding of FDA, EMA, and ICH regulations related to toxicology and cell and gene therapy development.
• Scientific writing, communication, presentation skills, and the ability to work independently in a collaborative matrixed environment.
• Applicants must be authorized to work in the United States; employment eligibility is verified through Form I-9 and E-Verify.

Nice to have

• Experience with cell therapy, gene therapy, biologics, or other advanced therapeutic platforms.
• Experience contributing to IND/CTA-enabling packages and global regulatory submissions.

Culture & Benefits

• Hybrid work environment within a global biotechnology organization.
• Medical, dental, and vision insurance.
• 401(k) retirement plan with a company match that fully vests on day one.
• Eight weeks of paid parental leave after three months of employment.
• Paid vacation, personal and sick time, floating holidays, and eleven company holidays.
• Additional benefits include flexible spending and health savings accounts, disability coverage, commuter benefits, family care resources, and well-being initiatives.