8 дней назад
Vice President, Biologics Research (Protein Engineering)
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Vice President, Biologics Research (Protein Engineering): Defining scientific strategy and leading biologics discovery and preclinical development across protein engineering, immunology, AAV, and gene therapy programs with an accent on translating research into clinical development. Focus on integrating computational biology, data science, laboratory automation, AI-enabled workflows, and multidisciplinary teams to advance candidates through IND-enabling studies and first-in-human readiness.
Location: Onsite in New Hampshire, United States, with flexibility for some remote work. Occasional travel of approximately 5%–15% is required.
Company
is a global biopharmaceutical company developing therapies for patients with serious and rare diseases.
What you will do
- Define and drive the long-term scientific strategy for biologics research in alignment with corporate and portfolio objectives.
- Provide scientific leadership across therapeutic targets, protein engineering, biologics modality selection, discovery, design, and development.
- Oversee discovery and preclinical milestones, including screening cascades, molecular design, candidate selection, and IND-enabling studies.
- Integrate computational biology, data science, experimental research, laboratory automation, and AI-enabled workflows.
- Support first-in-human readiness and collaborate with Clinical, Technical Operations, Toxicology, DMPK, Translational Bioanalytics, and Regulatory functions.
- Recruit, lead, and develop a biologics research organization of more than 50 scientists and staff across multiple research sites.
Requirements
- PhD or equivalent degree and 15 years of experience in biopharma or biotech R&D with progressive leadership responsibility.
- Deep expertise in protein engineering and knowledge of adaptive immunology, including human CD8+, CD4+, and B-cell responses to protein antigens.
- Experience with biotherapeutic drug development, in vivo pharmacology, PK/PD strategy, preclinical CMC support, toxicology and safety assessment, and first-in-human translation.
- Experience leading multidisciplinary teams and delivering high-impact programs in a matrixed, fast-paced environment.
- Strong executive communication, scientific judgment, and cross-functional collaboration skills.
Nice to have
- Familiarity with computational protein design and AI/ML-enabled protein design technologies.
- Experience with AAV viral vector engineering, AAV gene therapy discovery, computational biology, data science, or research bioprocess development.
Culture & Benefits
- Medical, dental, vision, and mental health coverage, plus annual wellbeing reimbursement and an Employee Assistance Program.
- Paid time off, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration.
- 401(k) with company match, annual equity awards, ESPP participation, and company-paid life and disability insurance.
- Learning programs, mentorship, networking, employee resource groups, service programs, and recognition opportunities.
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