Process Development Engineer II (Bioconjugation)

Location: Onsite in Tarrytown, New York, United States

Company

hirify.global is a biotechnology company that discovers, develops, and commercializes medicines for serious diseases.

What you will do

• Design and develop scalable, robust, controlled, GMP-ready bioconjugation and purification processes at the bench.
• Use statistical design of experiments to optimize conjugation reactions, purification operations, and analytical characterization.
• Collaborate with analytical and cross-functional teams to establish characterization methods and define development goals.
• Assess CDMOs and transfer processes to GMP manufacturing sites, supporting scale-up and manufacturing activities onsite.
• Develop predictive process models and novel at-line or in-line process analytical technologies.
• Prepare technology-transfer, regulatory, publication, report, and patent documentation, and present data to broad audiences.

Requirements

• Bachelor’s degree with 5–6 years of relevant experience, or a master’s degree with 3–4 years of relevant experience, in chemical engineering, biochemical engineering, or a related field.
• Hands-on experience with bioconjugation processes, including lysine-based, cysteine-based, or site-specific approaches.
• Knowledge of protein purification and downstream techniques such as chromatography, ultrafiltration/diafiltration, and membrane technologies.
• Experience with analytical characterization tools including electrophoresis, mass spectrometry, HPLC, and UV spectroscopy.
• Strong understanding of technology transfer, critical thinking, problem-solving, communication, and cross-functional collaboration.
• Ability to work onsite in Tarrytown, New York.

Nice to have

• Experience working with antibodies in the bioconjugates space.
• Experience developing predictive process models or process analytical technologies.

Culture & Benefits

• Inclusive workplace with a science-driven and collaborative environment.
• Opportunities to contribute to GMP manufacturing and the progression of medicines from clinical development to commercialization.
• Potential benefits include bonuses, equity awards, retirement benefits, health and wellness programs, insurance, paid time off, and family support.
• Commitment to reasonable accommodation during the recruitment process where required.