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21 час назад

Principal Scientist, Pharmaceutical Development

Формат работы
onsite
Тип работы
fulltime
Грейд
senior
Английский
b2
Страна
UK
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Текст:
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TL;DR
Principal Scientist, Pharmaceutical Development (Pharmaceutical Sciences): Designing and interpreting developability studies and formulation strategies to help progress novel small-molecule candidates toward medicines with an accent on physicochemical, solid-state, biopharmaceutic, and drug-delivery science. Focus on integrating experimental, computational, predictive, and AI-enabled approaches, leading client projects, and mentoring scientists.

Location: Cambridge, United Kingdom

Company

hirify.global provides clinical research services, commercial insights, and healthcare intelligence for the life sciences and healthcare industries.

What you will do

  • Design, oversee, and interpret developability, preformulation, and formulation studies for candidate progression.
  • Integrate physicochemical, solid-state, biopharmaceutic, formulation, computational, predictive, and AI-enabled data to support development decisions.
  • Translate experimental and AI-supported insights into scientifically robust recommendations for drug discovery teams and client programmes.
  • Recommend formulation and drug-development strategies for challenging small-molecule candidates, including oral and non-oral delivery approaches.
  • Lead pharmaceutical development projects from proposal through delivery and act as the primary scientific contact for clients.
  • Provide scientific leadership, support business development, and mentor junior scientists.

Requirements

  • Postgraduate degree in Pharmaceutical Sciences, Chemistry, or a related discipline.
  • Extensive industrial R&D experience in pharmaceutical development or drug discovery.
  • Experience designing and interpreting developability, preformulation, or formulation studies for novel small-molecule APIs.
  • Strong knowledge of physicochemical, biopharmaceutic, drug-delivery, and drug-discovery principles.
  • Experience leading scientific projects, influencing project direction, communicating complex scientific data, and mentoring colleagues.
  • Proactive approach, attention to detail, adaptability, and scientific project-management skills.

Nice to have

  • Model-informed, data-driven, computational, predictive, or AI-enabled formulation and developability experience.
  • Experience interpreting PK data and applying mechanistic approaches such as DCS or PBPK.
  • Knowledge of solubility, dissolution, absorption-risk evaluation, solid-form characterization, and enabling technologies such as spray drying, particle engineering, or lipid-based systems.
  • Experience with oral absorption enhancement, non-oral dosage routes, or Beyond Rule of 5 compounds.

Culture & Benefits

  • Join a growing Pharmaceutical Development function during a period of transformation.
  • Work with experts across Discovery, DMPK, CMC, and wider IQVIA scientific functions.
  • Help shape a science-led capability focused on developability, innovation, and client impact.
  • Work directly with global pharmaceutical and biotechnology clients.

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