21 час назад
Principal Scientist, Pharmaceutical Development
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Principal Scientist, Pharmaceutical Development (Pharmaceutical Sciences): Designing and interpreting developability studies and formulation strategies to help progress novel small-molecule candidates toward medicines with an accent on physicochemical, solid-state, biopharmaceutic, and drug-delivery science. Focus on integrating experimental, computational, predictive, and AI-enabled approaches, leading client projects, and mentoring scientists.
Location: Cambridge, United Kingdom
Company
provides clinical research services, commercial insights, and healthcare intelligence for the life sciences and healthcare industries.
What you will do
- Design, oversee, and interpret developability, preformulation, and formulation studies for candidate progression.
- Integrate physicochemical, solid-state, biopharmaceutic, formulation, computational, predictive, and AI-enabled data to support development decisions.
- Translate experimental and AI-supported insights into scientifically robust recommendations for drug discovery teams and client programmes.
- Recommend formulation and drug-development strategies for challenging small-molecule candidates, including oral and non-oral delivery approaches.
- Lead pharmaceutical development projects from proposal through delivery and act as the primary scientific contact for clients.
- Provide scientific leadership, support business development, and mentor junior scientists.
Requirements
- Postgraduate degree in Pharmaceutical Sciences, Chemistry, or a related discipline.
- Extensive industrial R&D experience in pharmaceutical development or drug discovery.
- Experience designing and interpreting developability, preformulation, or formulation studies for novel small-molecule APIs.
- Strong knowledge of physicochemical, biopharmaceutic, drug-delivery, and drug-discovery principles.
- Experience leading scientific projects, influencing project direction, communicating complex scientific data, and mentoring colleagues.
- Proactive approach, attention to detail, adaptability, and scientific project-management skills.
Nice to have
- Model-informed, data-driven, computational, predictive, or AI-enabled formulation and developability experience.
- Experience interpreting PK data and applying mechanistic approaches such as DCS or PBPK.
- Knowledge of solubility, dissolution, absorption-risk evaluation, solid-form characterization, and enabling technologies such as spray drying, particle engineering, or lipid-based systems.
- Experience with oral absorption enhancement, non-oral dosage routes, or Beyond Rule of 5 compounds.
Culture & Benefits
- Join a growing Pharmaceutical Development function during a period of transformation.
- Work with experts across Discovery, DMPK, CMC, and wider IQVIA scientific functions.
- Help shape a science-led capability focused on developability, innovation, and client impact.
- Work directly with global pharmaceutical and biotechnology clients.
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