Principal Analytical Sciences Scientist (Biotechnology)

Location: Rensselaer, New York, United States; onsite, Monday–Friday, 8:00 a.m.–4:30 p.m.

Salary: $108,000–$176,000 annually

Company

hirify.global features a role supporting Regeneron's analytical sciences, manufacturing, process sciences, and quality control activities.

What you will do

• Develop, optimize, troubleshoot, validate, transfer, and manage analytical methods for siRNA oligonucleotides and peptide therapeutics.
• Design and review assay qualification and validation protocols based on ICH Q2 principles, ensuring methods support GMP release and product characterization.
• Evaluate and implement analytical technologies including LCMS, capillary electrophoresis, ion-pair reverse-phase HPLC, hybridization-based assays, and peptide mapping.
• Transfer control test procedures to Quality Control and other departments by preparing transfer plans, training materials, and acceptance criteria.
• Lead troubleshooting, OOS/OOT investigations, deviation root-cause analysis, and customer complaint assessments.
• Represent Analytical Sciences in cross-functional teams, present technical findings, mentor junior staff, and maintain SOPs, protocols, and lifecycle documentation.

Requirements

• PhD in Chemistry, Biochemistry, Biology, or a related field.
• At least 3 years of relevant industry experience in analytical development and QC method lifecycle management.
• Demonstrated experience developing and validating methods for siRNA oligonucleotides and peptide therapeutics.
• Hands-on proficiency with LCMS/MS, capillary electrophoresis, ion-pair reverse-phase HPLC, peptide mapping, and oligonucleotide characterization assays.
• Experience with method transfer to QC, troubleshooting, OOS/OOT investigations, technical writing, data integrity, and cross-functional collaboration.
• Ability to work onsite in Rensselaer, New York, Monday through Friday, 8:00 a.m.–4:30 p.m.

Culture & Benefits

• Inclusive workplace and equal employment opportunity environment.
• Comprehensive rewards may include annual bonuses, equity awards, retirement benefits, 401(k) matching, health and wellness programs, insurance, paid time off, and family support benefits.
• Reasonable accommodations are available during the recruitment process where required.

Hiring process

• Background checks may verify identity, right to work, and educational qualifications in accordance with applicable law.
• Final level and offer depend on qualifications, skills, experience, country of employment, and role requirements.