Senior Scientist, Conjugation Process Development (Bioconjugation)

Location: On Premise in Bothell, Washington, US. Must be authorized to work in the U.S. without visa sponsorship.

Salary: $93,600 – $156,000

Company

Global research-based pharmaceutical company focused on delivering breakthroughs that change patients' lives through advanced science and technologies.

What you will do

• Lead ADC process development projects from early-phase clinical molecules through late-stage or commercial products.
• Independently design, execute, and interpret studies to solve defined scientific questions within set timeframes.
• Facilitate internal and external technology and assay transfers.
• Author and review technical reports, manufacturing documents, regulatory submissions, and publications.
• Identify areas for process improvement and propose innovative technology development solutions.
• Mentor team members and represent the group within multidisciplinary project teams.

Requirements

• PhD with 0-3 years of experience, Master's with 7-8 years, or Bachelor's with 9-11 years in chemistry, biochemistry, chemical engineering, or a related field.
• Direct experience with antibodies, proteins, and/or bioconjugation.
• Strong understanding of analytical protein characterization, including HPLC, IEF, and CE-SDS.
• Foundational knowledge of organic chemistry, reaction mechanisms, and process development.
• Permanent work authorization in the United States is required; visa sponsorship is not available.
• Willingness to work with highly potent cytotoxic molecules and perform complex data analysis.

Nice to have

• Experience with tangential flow filtration.
• Proficiency with statistical and data analysis software such as JMP for experimental design and visualization.
• Experience with GMP manufacturing and familiarity with CMC team functions.
• Experience with technology transfer to manufacturing.
• Knowledge of chemical synthesis and protein modification.

Culture & Benefits

• Comprehensive health benefits including medical, prescription drug, dental, and vision coverage.
• 401(k) plan with company matching and additional retirement savings contributions.
• Generous paid time off, including vacation, holiday, personal days, and caregiver/parental leave.
• Eligibility for the Global Performance Plan with a bonus target of 12.5% of base salary.
• Participation in a share-based long-term incentive program.