Senior Principal Machine Learning Scientist (AI Biology)

TL;DR

Senior Principal Machine Learning Scientist (AI Biology): Developing next-generation AI systems for biology to generate insights into disease mechanisms and therapeutic opportunities with an accent on genomics foundation models and multimodal biological data. Focus on designing state-of-the-art sequence modeling, self-supervised learning, and generative models to accelerate therapeutic innovation.

Location: South San Francisco, CA (Relocation benefits available)

Salary: $202,800 - $376,600

Company

A member of the Roche group and pioneer of the biotechnology industry dedicated to discovering and developing medicines for serious and life-threatening diseases.

What you will do

• Define the scientific roadmap and strategy for genomics foundation models to accelerate therapeutic innovation.
• Develop state-of-the-art sequence modeling, self-supervised learning, and generative models using multimodal biological data.
• Partner with experimental groups to translate machine learning innovation into insights for target discovery and disease understanding.
• Lead and mentor a team of scientists, fostering a culture of innovation and collaboration.
• Maintain scientific excellence by publishing in top-tier ML/genomics venues and representing the company at global conferences.
• Assess cutting-edge advancements in machine learning to identify new opportunities for scientific impact.

Requirements

• PhD in Computer Science, Machine Learning, Computational Biology, Physics, or a related quantitative field.
• Minimum 7 years of post-PhD research experience developing innovative AI/ML methods to advance biological discovery.
• Deep knowledge of foundation models, sequence modeling, self-supervised learning, generative AI, or multimodal ML.
• Expertise in gene regulation, epigenomics, functional genomics, regulatory biology, or cellular systems biology.
• Strong history of publishing novel computational methods in leading AI, ML, or genomics venues.
• Proven ability to lead complex scientific initiatives and influence across multiple disciplines.

Culture & Benefits

• Relocation benefits provided for the role.
• Discretionary annual bonus based on individual and company performance.
• Comprehensive benefits package provided by hirify.global.
• Work environment focused on scientific excellence, innovation, and transformative impact on patient health.