Research Associate (RNA Delivery)

TL;DR

Research Associate (RNA Delivery): Designing systems for mRNA delivery in the gastrointestinal tract with an accent on novel material synthesis (polymers and lipids) for the formulation development of mRNA nanoparticles. Focus on physicochemical properties and in vitro transfection.

Location: On-Site in Cambridge, MA

Salary: $65,000.00/yr - $91,667.00/yr

Company

The hirify.global of MIT and Harvard focuses on developing clinically relevant solutions to a host of challenges such as infectious diseases, metabolic diseases, and cancer.

What you will do

• Perform a wide range of molecular biology techniques, including DNA synthesis and purification, PCR, in vitro transcription (IVT), RNA purification, gel electrophoresis, ELISA, and Western blotting.
• Design and construct plasmids; conduct bacterial transformations and perform plasmid preparation and characterization.
• Culture and maintain diverse mammalian cell lines with a high degree of precision and reproducibility.
• Synthesize lipid nanoparticles (LNPs) and perform physicochemical characterization using techniques such as DLS and Ribogreen assays.
• Analyze, interpret, and present experimental data and research findings to internal teams and external collaborators.
• Supervise, train, and mentor junior team members.

Requirements

• B.S./M.S. or equivalent in biomedical engineering, chemical engineering, material science, pharmaceutical sciences, or a closely related field.
• 3+ years of experience in at least 2 of the following areas: Synthesis of polymers and/or lipids, Mammalian cell culture, General biological characterization techniques, Formulation development.
• Self-motivation and willingness to learn new tools and techniques.
• Strong organizational, interpersonal, and communication skills.
• Ability to work independently and as part of a team.
• Commitment to exceeding standards and producing accurate, high quality work.

Culture & Benefits

• Competitive benefits package including medical, dental, vision, life, and disability insurance.
• 401(k) retirement plan.
• Flexible spending and health savings accounts.
• At least 13 paid holidays.
• Paid time off; parental and family care leave; and an employee assistance program.