Principal Clinical Scientist, Medical Devices & AI

Location: Hybrid in New York, Los Angeles, San Francisco, Miami, or Washington, D.C.; remote-eligible within NY, NJ, CT, FL, CA, and Washington, DC.

Salary: $202.5K–$247.5K annually, plus equity.

Company

hirify.global develops proprietary sensors, algorithms, and clinical workflows for accessible, data-driven preventive healthcare delivered through its own clinics.

What you will do

• Set the scientific direction for evidence generation across medical devices, AI algorithms, and software as a medical device.
• Convert product bets and anchor use cases into testable hypotheses, evidence plans, and rigorous study protocols.
• Design novel clinical and validation studies when no established template exists, using AI in study design and analysis.
• Design studies for Neko’s clinics and ensure the resulting evidence supports product, regulatory, and scientific needs.
• Set methodological standards, challenge external and internal study designs, and mentor earlier-career scientists.
• Partner with product, engineering, data science, clinical operations, regulatory, and quality teams.

Requirements

• MD, PhD, or equivalent doctoral-level training in clinical research, epidemiology, physiology, biomedical engineering, biostatistics, medical AI, or a related field.
• At least 8 years designing and leading clinical or validation studies, including at least 4 years involving medical devices, diagnostics, digital health, or AI/SaMD.
• Evidence of taking a new concept from idea to evidence used in a product, regulatory submission, or clinical decision.
• Hands-on fluency with AI and data, including Python or R, modern machine learning and foundation-model evaluation, and daily use of large language models.
• Working knowledge of evidence requirements for regulatory and ethics pathways such as FDA, EU MDR, ISO 14155, and UK MHRA; regulatory affairs is not the core responsibility.
• Strong quantitative judgment covering sample size, endpoints, reference standards, analysis plans, diagnostic accuracy, and AI validation risks.
• Experience in a fast, product-led technology company, medtech scale-up, or applied research lab, with a clear preference for this environment.
• Remote work is limited to NY, NJ, CT, FL, CA, and Washington, DC.

Nice to have

• Experience with physiological sensing, imaging, or multimodal biomarker and AI validation.
• Experience running prospective studies across multiple sites or countries, including Europe and the US.
• Experience mentoring early-career scientists.
• Relevant publications and clear judgment about which publications matter for the product.

Culture & Benefits

• Hybrid work with remote eligibility in specified US locations.
• Equity included in the compensation package.
• Fast, product-led environment that accepts calculated risk while requiring rigorous science.
• The role focuses on scientific direction and study design rather than academic publication, strategy, regulatory submissions, study management, or monitoring.