Global Commercial Strategy (GCS) Oncology: Senior Director, Portfolio Strategy

Location: Hybrid in the United States, with listed locations in New York City, New York; Cambridge, Massachusetts; Bothell, Washington; and Collegeville, Pennsylvania. Candidates must have permanent authorization to work in the United States. Relocation assistance may be available based on business needs and eligibility.

Annual base salary: $214,900–$358,100. The role is also eligible for a 22.5% bonus target and a share-based long-term incentive program.

Company

hirify.global is a pharmaceutical and life sciences company developing medicines and therapies, including oncology treatments.

What you will do

• Lead the development and evolution of Oncology portfolio strategy, long-range scenarios, strategic roadmaps, and investment priorities across tumor types, mechanisms, modalities, and therapeutic platforms.
• Advise Oncology leadership on portfolio prioritization, capital allocation, development sequencing, indication expansion, lifecycle optimization, and strategic trade-offs.
• Integrate scientific, clinical, epidemiologic, access, policy, patient, competitive, commercial, and financial insights into portfolio recommendations and executive-ready reports, dashboards, and scenario plans.
• Lead cross-functional initiatives and governance preparation across Research, Development, Medical, Commercial, Access, Regulatory, Finance, Business Development, and related functions.
• Develop portfolio management frameworks, methodologies, governance processes, and decision-support capabilities, including AI-enabled approaches.
• Mentor colleagues, build team capabilities, and foster accountability, collaboration, learning, strategic thinking, innovation, and analytical rigor.

Requirements

• Bachelor's degree.
• 12+ years of progressive experience in pharmaceutical, biotechnology, life sciences, commercial development, portfolio strategy, business development, strategy consulting, corporate strategy, or related fields.
• Experience in Oncology.
• Experience leading enterprise-level strategic initiatives and influencing significant investment decisions.
• Experience leading highly visible, cross-functional initiatives in complex matrix organizations.
• Ability to synthesize scientific, clinical, commercial, competitive, and financial information to support portfolio prioritization and capital allocation decisions.
• Strong strategic, analytical, and financial acumen, including experience evaluating risk, uncertainty, and value creation across multiple opportunities.
• Track record of influencing senior leadership and aligning diverse stakeholder groups.
• Excellent communication, facilitation, organizational, and executive-ready storytelling skills.
• Ability to influence and collaborate with peers, develop and coach others, and oversee and guide colleagues to achieve meaningful outcomes and business impact.

Nice to have

• Advanced degree in business, life sciences, medicine, pharmacy, public health, or a related field.
• Experience developing long-range portfolio strategies across multiple disease areas, modalities, or therapeutic platforms.
• Experience supporting governance bodies, investment committees, or enterprise portfolio reviews.
• Experience shaping portfolio prioritization frameworks, resource allocation decisions, and strategic trade-off discussions.
• Experience assessing internal pipeline and external innovation opportunities, including licensing, partnerships, and acquisitions.
• Understanding of portfolio management, valuation methodologies, forecasting, and investment decision-making.
• Deep understanding of the oncology ecosystem, evolving standards of care, emerging science, competitive dynamics, and future market evolution.
• Experience evaluating opportunities across multiple tumor types and mechanisms.
• Ability to connect scientific innovation with portfolio-level value creation and strategic differentiation.
• Experience advising senior executives on complex strategic decisions with significant business impact.
• Ability to lead through ambiguity, navigate competing stakeholder priorities, and make recommendations with incomplete information.
• Experience establishing strategic frameworks, processes, or capabilities that improve organizational decision-making.
• Comfort operating in an AI-enabled or AI-augmented environment; experience using AI tools for strategy, synthesis, scenario planning, or analysis.
• Discretion, sound judgment, and trustworthiness when handling confidential or sensitive matters.

Culture & Benefits

• Hybrid work arrangement.
• Comprehensive benefits, including medical, prescription drug, dental, and vision coverage.
• 401(k) plan with hirify.global matching contributions and an additional retirement savings contribution.
• Paid vacation, holidays, personal days, caregiver/parental leave, and medical leave.
• Participation in the Global Performance Plan and share-based long-term incentive program.
• Work in a cross-functional, matrixed environment focused on strategic thinking, innovation, collaboration, and analytical rigor.