Senior / Principal Computational Biologist (Bioinformatics / Omics)

Location: San Francisco Bay Area, United States; on-site

Salary: $235,000–$270,000 per year, plus equity

Company

hirify.global is a frontier research lab developing brain-computer interfaces that connect biological systems with advanced AI.

What you will do

• Design, deploy, optimize, and maintain large-scale pipelines for genomics, transcriptomics, and proteomics data.
• Architect data-processing frameworks that transform raw omics data into clean, analysis-ready datasets.
• Integrate multimodal biological data with machine learning models to uncover mechanistic and predictive insights.
• Collaborate with wet-lab scientists to define optimization objectives and encode domain-specific priors and constraints.
• Prototype, benchmark, and validate modeling frameworks using internal and public datasets.
• Contribute to research roadmaps, novel algorithms, discovery workflows, and first-principles analysis for non-domain experts.

Requirements

• Deep experience analyzing bulk and single-cell omics data and building bioinformatics pipelines.
• Expertise in Python and/or R, with fluency in workflow management tools such as Nextflow or Dagster.
• Proficiency in Python, PyTorch, and JAX, with the ability to write clean, reproducible, production-grade code.
• Experience bridging computational biology and experimental science with sparse, noisy, or high-cost data.
• Collaborative, systems-level mindset.
• Ability to work on-site in the San Francisco Bay Area.

Nice to have

• Familiarity with neuroscience.
• Familiarity with transfer-learning paradigms.

Culture & Benefits

• Interdisciplinary collaboration across molecular engineering, synthetic biology, neuroscience, engineering, and data science.
• Opportunity to work on high-bandwidth brain-computer interface technologies and advanced biological systems.
• Equity included in the compensation package.
• Commitment to equal opportunity and reasonable accommodations.