Research Assistant (Functional Genomics)

Location: Oxford Road, Manchester, United Kingdom. Hybrid working arrangements may be considered.

Company

The hirify.global's Rice Lab conducts functional genomics research within the Division of Musculoskeletal and Dermatological Sciences.

What you will do

• Deliver a defined two-year experimental research programme under the direction of Dr Sarah Rice.
• Plan and prioritise day-to-day experimental work and discuss progress and priorities regularly.
• Culture and maintain established human cell lines, mesenchymal stromal cells and primary human cells using aseptic technique.
• Generate and validate targeted regulatory-element deletions and other experimental cell models using CRISPR-Cas9 genome editing.
• Process human joint tissues obtained through clinical collaborators and investigate regulatory-element deletion during osteogenic and chondrogenic differentiation.

Requirements

• Knowledge of mammalian cell culture, aseptic technique and core molecular biology principles.
• Ability to plan and prioritise multi-stage experimental work and deliver reproducible results.
• Ability to analyse, interpret and clearly present experimental data in written and oral formats.
• Careful, proactive and collaborative approach, with the ability to work independently and troubleshoot experiments.

Nice to have

• Experience of primary human cell culture and/or processing human tissue samples.
• Experience of mesenchymal stromal or stem cell culture.
• Experience of osteogenic or chondrogenic differentiation.
• Experience of genome editing.

Culture & Benefits

• Inclusive workplace welcoming diverse perspectives and backgrounds.
• Market-leading pension scheme.
• Employee health and wellbeing services, including an Employee Assistance Programme.
• Generous annual leave entitlement, bank holidays and additional paid closure over Christmas.
• Local and national discounts at major retailers.

Hiring process

• The vacancy closes at midnight on the stated closing date.
• Individual application feedback cannot be provided because of the volume of applications.