9 дней назад
Director, Bioprocess Development (Biologics)
185 000 - 252 500$
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Director, Bioprocess Development (Biologics): Building and leading upstream and downstream bioprocess development capabilities, laboratories, and teams for biotherapeutic programs from discovery through preclinical CMC with an accent on recombinant protein expression, cell culture, purification, and scalable process development. Focus on designing robust processes, transferring technology to technical operations or CDMOs, and coordinating complex biologics programs across research and CMC functions.
Location: Lebanon, New Hampshire, United States; full-time, in-person presence required
Salary: $185,000–$252,500 annual
Company
is a global biopharmaceutical company developing treatments for patients with serious and rare diseases.
What you will do
- Build, lead, and mentor a high-performing bioprocess development team.
- Design and oversee state-of-the-art research laboratories, equipment strategies, and upstream and downstream processing capabilities.
- Develop scalable processes for microbial and mammalian expression, cell culture, purification, filtration, chromatography, and buffer exchange.
- Lead experimental design, execution, troubleshooting, data interpretation, protocols, reports, and technical documentation.
- Support multiple biologics programs, including enzymes, antibodies, fusion proteins, and other biotherapeutic modalities.
- Collaborate with Discovery, Analytical, Technical Operations, Preclinical Development, CMC teams, and external partners on candidate selection, tech transfer, scale-up, and manufacturability.
Requirements
- PhD in chemical engineering, biochemical engineering, biology, or a related field with 5+ years of industry experience, or an M.S. with 8+ years of industry experience.
- Demonstrated biologics process development experience in biotechnology or pharmaceutical settings, covering both upstream and downstream development.
- Hands-on expertise with microbial expression, including E. coli, mammalian expression, bench-scale bioreactor operations, scale-up, protein purification, and process characterization.
- Experience with preclinical CMC, commercial expression strain development, and technology transfer to technical operations groups or CDMOs.
- Proven experience building and leading teams, managing multiple programs, mentoring people, and collaborating across functions.
- Ability to work full-time in person at the Lebanon, NH office to support hands-on collaboration, specialized equipment access, and operational needs.
Nice to have
- Experience building laboratories and selecting capital equipment.
- Exposure to early GMP considerations.
- Familiarity with enzymes, monoclonal antibodies, bispecifics, engineered proteins, or half-life extension technologies.
Culture & Benefits
- Purpose-driven work focused on serious and rare diseases.
- Medical, dental, and vision coverage, mental health support, wellbeing reimbursement, and an Employee Assistance Program.
- Paid time off, fertility and family-forming benefits, caregiver support, and flexible schedules supporting purposeful in-person collaboration.
- 401(k) with company match, annual equity awards, employee stock purchase plan, and company-paid life and disability insurance.
- Learning programs, mentorship, employee resource groups, service opportunities, and recognition programs.
Hiring process
- Applications are accepted for five calendar days from the posting date or until the position is filled.
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