Process Development Senior Principal Scientist (ADC Biologics)

Location: Thousand Oaks, California, United States; onsite role with up to 10% domestic and international travel.

Company

hirify.global is a biotechnology company developing, manufacturing, and delivering medicines for serious illnesses across oncology, inflammation, general medicine, and rare disease.

What you will do

• Lead laboratory studies for drug product design, formulation, process development, documentation, and technology transfer.
• Develop and characterize liquid and lyophilized biologic formulations, with emphasis on ADC drug products and lab-scale sterile filling.
• Integrate formulation, analytical, stability, and process data to guide product design and commercialization.
• Lead internal and external technology transfers, process-fit assessments, CMO/CDMO collaboration, and manufacturing troubleshooting.
• Apply AI, machine learning, and data science to predictive modeling, workflow acceleration, and decision-making.
• Lead matrixed drug product teams and manage engineers and scientists supporting commercialization and lifecycle management.

Requirements

• PhD, PharmD, or MD plus 2 years of scientific experience; or a master’s degree plus 5 years; or a bachelor’s degree plus 7 years.
• Experience in pharmaceutical or biotechnology development, including formulation, fill/finish process development, process characterization, technology transfer, and design of experiments.
• Direct ADC drug product formulation experience is strongly preferred, including linker-payload stability, drug-to-antibody ratio, degradation pathways, quality attributes, and comparability.
• Strong knowledge of biologic formulation, stability testing, aseptic processing, manufacturing, analytical and biophysical techniques, and regulatory authoring.
• Experience with programming and data tools such as Python, R, MATLAB, SQL, Tableau, Spotfire, or D3, plus statistical software such as SAS, JMP, or Minitab.
• Ability to lead global multifunctional teams, solve complex problems, influence stakeholders, and learn new technologies rapidly.

Culture & Benefits

• Collaborative, innovative, science-based environment focused on serving patients.
• Health, dental, vision, life, disability, and flexible spending benefits.
• Retirement and savings plan with company contributions and stock-based long-term incentives.
• Discretionary annual bonus program and award-winning time-off plans.
• Career development opportunities and flexible work models where applicable.
• Visa sponsorship is not guaranteed.