3 дня назад
Associate Director, Translational Science (Cell Therapy)
168 372 - 220 988$
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Associate Director, Translational Science (Cell Therapy): Designing and executing translational strategies for cell therapy programs from lead optimization through Phase II trials with an accent on biomarker development, immunology, and multi-omic data integration. Focus on analyzing high-dimensional datasets, identifying patient stratification and drug-resistance signatures, and implementing biomarker assays in clinical protocols.
Location: Hybrid role based in Somerset, New Jersey, United States
Salary: $168,372–$220,988 USD annually, plus performance-based bonus and/or equity for eligible roles.
Company
is a global biotechnology company developing cell therapies, including autologous, allogeneic, and in vivo approaches, for life-threatening diseases.
What you will do
- Lead program-specific translational plans from lead optimization through Phase II clinical trials.
- Oversee analysis and integration of high-dimensional datasets, including scRNA-seq, CITE-seq, flow cytometry, and spatial transcriptomics.
- Identify pharmacodynamic markers, predictive signatures, mechanisms of action, patient stratification factors, and drug-resistance insights.
- Partner with Clinical Development and Clinical Operations to implement biomarker assays in clinical protocols and ensure high-quality data collection.
- Manage CRO and academic collaborations for specialized assay development and advanced data processing.
- Represent Translational Science on program teams and author technical reports, regulatory documents, publications, and conference materials.
Requirements
- PhD or MD/PhD in Immunology, Bioinformatics, Computational Biology, or a related field.
- At least 5 years of biopharmaceutical industry experience or equivalent academic leadership in translational research.
- Extensive knowledge of human autoimmune and oncology diseases, immuno-oncology, autoimmune disease, or cell therapy such as CAR-T or TCR-T.
- Hands-on experience with genomic data analysis pipelines and integration of multiple datasets.
- Proven experience developing, validating, and clinically implementing complex biomarkers.
- Must be authorized to work in the United States; employment eligibility is verified through Form I-9 and E-Verify.
Culture & Benefits
- Medical, dental, and vision insurance with a 401(k) company match vesting fully on day one.
- Eight weeks of paid parental leave after three months of employment.
- Paid vacation, personal time, sick time, floating holidays, and eleven company holidays.
- Flexible spending and health savings accounts, disability coverage, life insurance, legal assistance, and supplemental benefits.
- Family planning and care resources, well-being initiatives, commuter benefits, and peer-to-peer recognition programs.
- Benefits are available exclusively to permanent full-time employees; contractors are not eligible.
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