Associate Director, Chemical Engineering (Biotech)

Location: Brisbane, California, United States — onsite; travel up to 25% of the time.

Salary: $189,800–$216,700 per year

Company

hirify.global is a clinical-stage biopharmaceutical company developing targeted protein degradation medicines for cancer and inflammatory diseases using an AI-integrated discovery engine.

What you will do

• Provide chemical engineering leadership for scalable small-molecule drug substance manufacturing routes, including unit operation design, process modeling, equipment selection, and scale-up.
• Oversee facility and equipment operations at external CDMOs, including qualification, maintenance, engineering support, and performance monitoring.
• Lead technology transfer, process troubleshooting, engineering batches, clinical and registration batches, PPQ batches, and commercial scale-up activities.
• Partner with CMC, Quality Assurance, and Global Supply Chain teams to support timely drug substance manufacture and lot release.
• Drive process understanding using critical process parameters, critical quality attributes, control strategy, DoE, and QbD principles.
• Review manufacturing documentation and regulatory filings, define long-term engineering strategy, and mentor scientists and engineers.

Requirements

• Ph.D. in chemical engineering or a related field with at least 5 years of relevant industrial experience; alternatively, an M.S. with 10 years or a B.S. with 15 years of experience.
• Extensive experience in GMP drug substance manufacturing, process development, equipment evaluation, scale-up, process validation, and small-molecule development.
• Knowledge of solid-state properties, polymorphism, and crystallization principles.
• Significant experience managing third-party drug substance CDMOs, including technology transfer, QbD and DoE studies, clinical supply, registration batches, and commercial launches.
• In-depth knowledge of cGMP, ICH, FDA, and EMA guidelines, plus strong communication, collaboration, problem-solving, and conflict-management skills.
• Ability to work onsite in Brisbane, California and travel up to 25%.

Culture & Benefits

• Highly collaborative, team-oriented environment.
• Solutions- and results-oriented culture.
• Hands-on, resourceful approach with openness to diverse perspectives.
• Opportunity to contribute across late-stage development, commercial launch, and lifecycle management.