Associate Director, Clinical Pharmacology

Location: New York City, United States; hybrid role requiring residence within commuting distance and on-site work an average of 2.5 days per week or more as needed.

Annual base salary: $139,100–$231,900, plus a 17.5% bonus target and eligibility for a share-based long-term incentive program.

Company

hirify.global is a pharmaceutical company developing medicines through clinical research and model-informed drug development.

What you will do

• Represent Clinical Pharmacology on clinical sub-teams, development teams, and other multifunctional project teams.
• Design and execute clinical pharmacology plans and deliverables for Internal Medicine projects.
• Plan and oversee PK/PD analyses, immunogenicity and biomarker strategies, study protocols, clinical phase activities, and reporting.
• Develop dose-ranging strategies and optimize doses, dosage regimens, and study designs using quantitative pharmacology.
• Lead end-to-end MIDD plans and contribute to regulatory documents, including IND, NDA/MAA, investigator’s brochures, briefing documents, and regulatory responses.
• Develop new methodologies, collaborate with external experts, coach colleagues, and represent the field through publications and presentations.

Requirements

• MD, PhD, PharmD, or equivalent training and experience in pharmacokinetics, pharmacometrics, clinical pharmacology, engineering, or a related discipline.
• At least 5 years of industry experience in clinical pharmacology, clinical PK/PD, pharmacometrics, or systems pharmacology.
• Strong quantitative expertise in mechanistic PK/PD modeling, systems pharmacology, population modeling, literature meta-analyses, and clinical trial simulations.
• Experience with NONMEM, R, or comparable quantitative pharmacology tools.
• Knowledge of drug development and quantitative approaches to knowledge integration, along with strong written, verbal, and presentation skills.
• Permanent authorization to work in the United States is required; U.S. work visa sponsorship is not available now or in the future.

Nice to have

• Experience developing methodologies through collaboration with external experts and scientific organizations.
• Ability to attend global meetings periodically across different time zones.

Culture & Benefits

• Hybrid work arrangement with regular on-site collaboration.
• Comprehensive medical, prescription drug, dental, and vision coverage.
• 401(k) plan with matching contributions and an additional retirement savings contribution.
• Paid vacation, holidays, personal days, caregiver/parental leave, and medical leave.
• Relocation assistance may be available based on business needs and eligibility.