Manufacturing Supervisor (Biopharma)

Location: USA - NC - Durham - Hamlin Rd. Full-time, onsite night shift with 12-hour shifts on a 2-2-3 schedule, including weekends, holidays, and overnight work.

Salary: Not specified.

Company

hirify.global operates biopharmaceutical manufacturing facilities producing bulk intermediates and drug substances.

What you will do

• Lead manufacturing associates in preparing solutions and growth media for upstream and downstream biopharmaceutical processing.
• Plan, assign, and monitor daily production activities to support schedule adherence and right-first-time execution.
• Review batch documentation and logbooks, initiate deviations, and complete ERP orders and corrections.
• Coach, mentor, train, and qualify team members while maintaining procedure and quality compliance.
• Oversee equipment and facility readiness, cleaning, maintenance activities, and work orders.
• Author and review SOPs and manufacturing records, troubleshoot operations, and drive process improvements, CAPAs, deviations, and change controls.

Requirements

• Bachelor’s degree in a related scientific or engineering discipline with 4 years of related cGMP manufacturing experience, or a high school degree with 10 years of experience, or equivalent.
• Demonstrated knowledge of biopharmaceutical manufacturing operations, including mammalian cell culture, microbial fermentation, or purification.
• Working knowledge of upstream or downstream bioprocessing equipment, production equipment, in-process testing instruments, ERP, EDMS, and MS Office.
• Fluent English reading, writing, speaking, and listening skills are required.
• Ability to work in a clean-room environment, wear clean-room attire, follow hygiene requirements, and handle mechanical, chemical, electrical, noise, lifting, and other physical demands.

Nice to have

• Experience with single-use platform technology.
• Knowledge of quality systems and regulatory expectations.

Culture & Benefits

• 12-hour night shifts following a 2-2-3 schedule.
• Work in a cGMP biotechnology manufacturing facility with cross-functional collaboration across manufacturing, MS&T, process development, QA, maintenance, facilities, AFS, and microbiology.
• Responsibilities include supporting safety, quality, delivery, engagement, cost, and continuous improvement objectives.