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1 день назад

Senior Scientist, Drug Product Development (Small Molecules)

139 000 - 169 000$
Формат работы
onsite
Тип работы
fulltime
Грейд
senior
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

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TL;DR
Senior Scientist, Drug Product Development (Small Molecules) (Pharmaceutical Development): Developing pre-formulation packages, solid oral dosage forms, and manufacturing processes for small-molecule drug candidates with an accent on physicochemical characterization, formulation selection, and clinical material production. Focus on optimizing poorly water-soluble compounds, overseeing CDMOs, supporting CMC regulatory filings, and managing development risks across clinical timelines.

Location: South San Francisco, CA, United States; onsite with three to five days per week in the lab. Remote applicants are not being considered.

Salary: $139,000–$169,000 USD annually

Company

hirify.global is a precision medicines company developing treatments intended to transform outcomes for patients with autoimmune diseases.

What you will do

  • Develop pre-formulation packages and formulations for small-molecule drug candidates, including poorly water-soluble compounds.
  • Identify vehicles, excipients, and technologies supporting preclinical PKPD, efficacy, and toxicology studies.
  • Characterize physicochemical and solid-state properties using HPLC/UPLC, DSC, and XRPD, while developing analytical methods.
  • Develop and optimize formulations and manufacturing processes for solid oral dosage forms, including modified-release products.
  • Collaborate with external CDMOs and oversee clinical trial material production against development timelines.
  • Support CMC sections of IND and NDA filings, technical reports, risk mitigation, and contingency planning.

Requirements

  • Ph.D. in Pharmaceutical Sciences, Chemistry, Engineering, or a related field with at least 8 years of experience, or a B.S./M.S. with 10+ years of related industrial experience.
  • Hands-on experience with pre-formulation, formulation development, process optimization, and instrumental analysis.
  • Experience developing small-molecule solid oral dosage forms and working with external CDMOs.
  • Clear oral and written communication skills and the ability to work in a fast-paced, collaborative environment.
  • Willingness to travel as needed to support development activities.

Culture & Benefits

  • Collaborative, dynamic environment guided by the values Elevate, Challenge, and Nurture.
  • Stock option grants and an annual bonus program.
  • Health insurance premiums covered at 90% for employees and 80% for dependents.
  • Unlimited PTO for exempt employees, an onsite gym, and a stocked kitchen.
  • Free access to the Genentech Bus & Ferry Share program and a $100 monthly cell phone stipend.

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