Medical Director, Drug Safety and Pharmacovigilance

Location: South San Francisco, California; onsite four days per week, with work-from-home flexibility.

Salary: $268,000–$331,000 per year.

Company

hirify.global is a public, clinical-stage precision medicine oncology company developing targeted therapies for genetically defined cancer patient populations.

What you will do

• Lead and oversee medical review of individual case safety reports, including complex and medically significant oncology cases.
• Assess adverse events for causality, seriousness, expectedness, and clinical accuracy of case narratives.
• Serve as the primary medical contact for the pharmacovigilance vendor and provide input on case quality, triage, and regulatory submission compliance.
• Monitor case-processing quality metrics, investigate deviations and quality events, and support CAPA development and tracking.
• Participate in vendor governance meetings and support regulatory inspections, audits, and health authority inquiries.
• Contribute to SOPs, medical review guidelines, training materials, aggregate safety reports, protocol amendments, investigator brochures, and informed consent documents.

Requirements

• MD or equivalent international medical degree with at least two years of bedside clinical experience.
• 5–8+ years of oncology experience in drug safety or pharmacovigilance.
• Strong hands-on experience with ICSR medical review.
• Experience working with external pharmacovigilance vendors or CROs.
• Strong knowledge of global pharmacovigilance regulations, including FDA, EMA, and ICH requirements.
• Strong medical judgment, attention to detail, and ability to work effectively in a matrix environment.

Culture & Benefits

• Collaborative, inclusive, data-driven environment focused on advancing precision oncology therapies.
• Medical, dental, and vision coverage, with the company paying 100% for employees and 90% for dependents.
• 401(k), employee stock purchase plan, wellness programs, and eligibility for discretionary incentive and stock option awards.
• Employees working in company facilities must be fully vaccinated against COVID-19, subject to applicable accommodations.