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4 дня назад

Head of DMPK (TechBio)

155 300 - 194 600GBP
Формат работы
hybrid
Тип работы
fulltime
Грейд
head
Английский
b2
Страна
UK
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

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TL;DR
Head of DMPK (TechBio): Leading the DMPK strategy to transition programs from hit-identification through to IND-enabling studies with an accent on predictive modeling and high-throughput data integration. Focus on building high-performing teams, driving scientific rigor in human dose projections, and collaborating with AI/ML teams to de-risk the drug discovery portfolio.

Location: Must be based in or able to work from our London, England office (hybrid, 50% in-office)

Salary: £155,300–£194,600 per year

Company

hirify.global is a clinical-stage TechBio company decoding biology to radically improve lives through an AI-native, end-to-end drug discovery platform.

What you will do

  • Define and execute the overarching DMPK strategy for a diverse therapeutic portfolio.
  • Ensure scientific excellence in human dose projections, DDI assessments, and translational PK/PD strategies.
  • Partner with Data Science and ML teams to refine predictive ADME models and prioritize compounds.
  • Act as a strategic subject matter expert for high-stakes external partnerships.
  • Develop and lead a high-performing team, fostering an environment of rapid adaptation.
  • Integrate DMPK insights into multidisciplinary project teams from target validation through lead optimization.

Requirements

  • PhD in Pharmacokinetics, Drug Metabolism, Pharmacology, or a related field.
  • 15+ years of experience in the pharmaceutical or biotech industry moving programs from Discovery into Development.
  • Deep expertise in small molecule DMPK and familiarity with modalities like ADCs or peptides.
  • Proven history of navigating regulatory interactions and IND submission requirements.
  • Strong collaborative leadership skills with experience influencing cross-functional stakeholders.
  • Proficiency in managing CROs to ensure high-quality data delivery.

Culture & Benefits

  • Competitive base salary with annual bonus and equity compensation.
  • Comprehensive benefits package.
  • Opportunity to work at the intersection of biology and cutting-edge computational technology.
  • Collaborative, mission-driven environment focused on patient impact.
  • Commitment to diversity and equal opportunity employment.

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