4 дня назад
Head of DMPK (TechBio)
155 300 - 194 600GBP
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Head of DMPK (TechBio): Leading the DMPK strategy to transition programs from hit-identification through to IND-enabling studies with an accent on predictive modeling and high-throughput data integration. Focus on building high-performing teams, driving scientific rigor in human dose projections, and collaborating with AI/ML teams to de-risk the drug discovery portfolio.
Location: Must be based in or able to work from our London, England office (hybrid, 50% in-office)
Salary: £155,300–£194,600 per year
Company
is a clinical-stage TechBio company decoding biology to radically improve lives through an AI-native, end-to-end drug discovery platform.
What you will do
- Define and execute the overarching DMPK strategy for a diverse therapeutic portfolio.
- Ensure scientific excellence in human dose projections, DDI assessments, and translational PK/PD strategies.
- Partner with Data Science and ML teams to refine predictive ADME models and prioritize compounds.
- Act as a strategic subject matter expert for high-stakes external partnerships.
- Develop and lead a high-performing team, fostering an environment of rapid adaptation.
- Integrate DMPK insights into multidisciplinary project teams from target validation through lead optimization.
Requirements
- PhD in Pharmacokinetics, Drug Metabolism, Pharmacology, or a related field.
- 15+ years of experience in the pharmaceutical or biotech industry moving programs from Discovery into Development.
- Deep expertise in small molecule DMPK and familiarity with modalities like ADCs or peptides.
- Proven history of navigating regulatory interactions and IND submission requirements.
- Strong collaborative leadership skills with experience influencing cross-functional stakeholders.
- Proficiency in managing CROs to ensure high-quality data delivery.
Culture & Benefits
- Competitive base salary with annual bonus and equity compensation.
- Comprehensive benefits package.
- Opportunity to work at the intersection of biology and cutting-edge computational technology.
- Collaborative, mission-driven environment focused on patient impact.
- Commitment to diversity and equal opportunity employment.
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