Executive Director, Translational & Computational Biology (AI)

Location: Hybrid; must live within commuting distance of a hirify.global location and work on-site an average of 2.5 days per week. Positions are available in Bothell, Washington, and New York City, New York. Permanent work authorization in the United States is required.

Annual base salary: $230,900–$384,800, plus eligibility for a 25% bonus target and share-based long-term incentive program.

Company

hirify.global develops medicines and is expanding AI and data capabilities across research and development to improve drug discovery and clinical development decisions.

What you will do

• Lead a portfolio of high-value biological, translational, and clinical questions across R&D.
• Connect therapeutic-area, translational, clinical, computational biology, engineering, statistics, and AI teams.
• Define analytical and AI strategies, including cohorts, endpoints, labels, annotations, evaluation criteria, study design, and validation plans.
• Guide work involving multi-omics, single-cell and spatial biology, genetics and genomics, perturbational biology, imaging, digital pathology, clinical trials, real-world evidence, literature, and other multimodal data.
• Interpret complex evidence in biological and clinical context, assess uncertainty, bias, confounding, robustness, and generalizability, and translate findings into scientific recommendations.
• Influence discovery, translational, clinical, development, and portfolio decisions while scaling successful AI-enabled approaches across R&D.

Requirements

• PhD, MD, PharmD, or equivalent advanced degree in computational biology, translational biology, bioinformatics, genetics, genomics, systems biology, biomedical sciences, biostatistics, or a related discipline with 10+ years of relevant industry or research experience; or a master’s degree with 12+ years of relevant experience, or an equivalent record of scientific and translational impact.
• Sustained experience translating complex biological and clinical data into insights that influenced scientific, development, or portfolio decisions.
• Experience leading cross-functional scientific or translational programs from ambiguous questions to evidence-based decisions and setting strategy for complex analytical, biomarker, precision-medicine, or data-driven work.
• Experience applying computational and quantitative approaches to biological and clinical questions, influencing senior stakeholders, and operating autonomously in matrixed organizations.
• Working or strong proficiency in R and/or Python, or equivalent computational tools; statistical reasoning; experimental design; quantitative interpretation; biological and clinical data analysis; and visualization.
• Knowledge of reproducible research, evidence generation, machine learning and AI concepts relevant to biomedical research, and evaluation of model outputs, uncertainty, limitations, and scientific validity.
• Scientific depth in at least one area including multi-omics, single-cell or spatial biology, genetics and genomics, translational or systems biology, imaging or digital pathology, clinical development and biomarker science, or real-world data and evidence.
• Demonstrated strategic thinking, biological judgment, scientific rigor, executive-level communication, cross-functional influence, and ability to work with ambiguity and high autonomy.

Nice to have

• Significant biotechnology or pharmaceutical R&D experience.
• Impact across drug discovery, translational research, clinical development, precision medicine, or biomarker strategy.
• Experience applying or adopting AI-enabled scientific workflows in real R&D settings.
• Experience leading multidisciplinary teams or major cross-functional workstreams.
• Deep therapeutic-area expertise and experience translating computational evidence into program or portfolio decisions.

Culture & Benefits

• Senior-level scientific ownership and autonomy across high-value problems spanning discovery through clinical development.
• Access to biomedical and clinical data, advanced AI capabilities, and collaboration with therapeutic-area, clinical, technical, and senior R&D leaders.
• Comprehensive benefits including a 401(k) with hirify.global matching and additional retirement contributions, paid vacation, holidays, personal days, caregiver/parental and medical leave, and medical, prescription, dental, and vision coverage.
• Relocation assistance may be available based on business needs and eligibility.
• Compensation and benefits are aligned with the location of hire; the stated salary range does not apply to Tampa, Florida, or locations outside the United States.