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8 дней назад

Associate Scientist, Drug Formulation (Nanoparticle Drug Delivery)

103 000 - 131 000$
Формат работы
onsite
Тип работы
fulltime
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

Текст:
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TL;DR
Associate Scientist, Drug Formulation (Nanoparticle Drug Delivery): Developing and characterizing nanoparticle-based drug delivery systems for RNA/gene-based therapies with an accent on lipid nanoparticles, nucleic acid encapsulation, and physicochemical analysis. Focus on designing formulation studies, optimizing compositions, evaluating bioconjugates, and solving formulation challenges through data-driven experimentation.

Location: Bridgewater, New Jersey, US; full-time, in-person presence required at the Bridgewater office.

Salary: $103,000–$131,000 annual.

Company

hirify.global is a global biopharmaceutical company developing therapies for patients with serious and rare diseases.

What you will do

  • Develop, optimize, and characterize lipid nanoparticles and other nanoparticle-based delivery systems for platform and project support.
  • Design and execute formulation studies, including nucleic acid encapsulation, analytical testing, stability evaluations, and formulation optimization.
  • Characterize nanoparticle physicochemical properties, including size, PDI, zeta potential, encapsulation efficiency, drug loading, and release kinetics.
  • Apply DLS, NTA, UV-Vis, SEC, SDS-PAGE, HPLC, and fluorescence-based assays to evaluate nanoparticles and drug products.
  • Support the design, synthesis, purification, and characterization of protein bioconjugates, including monoclonal antibody, peptide, and dye conjugates.
  • Analyze data, troubleshoot formulation challenges, document results in electronic notebooks, and prepare technical reports.

Requirements

  • Master’s degree in Pharmaceutics, Chemistry, Biomedical Engineering, Chemical Engineering, or a related field; or a bachelor’s degree plus 2 years of experience in one of these fields.
  • Hands-on experience in nanoparticle-based formulation development and analytical characterization.
  • Ability to perform formulation and characterization work supporting RNA/gene-based therapeutic programs.
  • Ability to maintain accurate, detailed, and timely experimental records and generate internal technical reports.

Nice to have

  • Experience with nucleic acid delivery systems, especially lipid-based or polymeric nanoparticles, and nucleic acid encapsulation.
  • Experience with bioconjugates and targeted delivery.
  • Experience with DLS, NTA, SEC, UV-Vis spectroscopy, HPLC, SDS-PAGE, fluorescence assays, and protein quantification.
  • Strong data analysis skills using GraphPad Prism, Excel, or similar tools.
  • Familiarity with stability testing, release profiling, formulation optimization, statistics, and data interpretation.
  • Ability to independently design, execute, interpret, and present experimental results.

Culture & Benefits

  • Purpose-driven biopharmaceutical environment focused on serious and rare diseases.
  • Full-time in-person collaboration with access to specialized equipment; minimal travel expected.
  • Medical, dental, vision, mental health, wellbeing, paid time off, fertility and family-forming, and caregiver benefits.
  • 401(k) with company match, annual equity awards, ESPP, life and disability insurance, and learning programs.
  • Employee resource groups, mentorship, networking, service, and recognition programs.

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