Principal Scientist - Clinical Research, Immunology Biomarker Lead (Immunology)

Location: Hybrid role available in Cambridge, Boston, Rahway, or West Point, United States. Domestic relocation is indicated; travel requirements are 10%.

Salary: $190,800–$300,300 per year for the primary location, plus eligibility for an annual bonus and long-term incentive where applicable.

Company

hirify.global develops medicines and advances clinical research across complex disease areas.

What you will do

• Lead integrated biomarker strategies across discovery and early- and late-stage clinical programs.
• Connect drug mechanism, disease biology, precision medicine, pharmacodynamics, dose decisions, and clinical endpoints to development decisions.
• Serve as biomarker strategy lead for cross-functional program teams and represent multidisciplinary teams in governance forums.
• Lead biomarker sub-teams involving clinical, discovery, translational, regulatory, biostatistics, and data sciences functions.
• Direct biomarker analysis plans and interpret complex datasets to produce scientifically rigorous, clinically meaningful conclusions.
• Communicate insights to internal stakeholders, governance bodies, external scientific audiences, and KOLs through publications and presentations.

Requirements

• PhD or MD in Immunology, Biology, or a related STEM field with 7+ years of immunology experience; alternatively, an MS with 10+ years or a BS with 14+ years of experience.
• Deep expertise in immunology and immune-mediated or inflammatory diseases, including experience in rheumatology, gastrointestinal or mucosal inflammation, or dermatology.
• Proven experience driving translational strategies that inform clinical development decisions and collaborating across functions.
• Demonstrated ability to lead highly matrixed teams and influence cross-functional stakeholders.
• Strong analytical and problem-solving capabilities, including translating complex data into clear, decision-oriented insights.
• Excellent communication skills.
• Working knowledge of biostatistics, bioinformatics, and advanced data analytics.
• Experience advancing precision medicine strategies.
• Strategic, decision-focused approach and ability to operate effectively in a fast-moving, matrixed environment.

Nice to have

• Experience in autoimmune diseases R&D and/or translational medicine.

Culture & Benefits

• Hybrid work arrangement with regular cross-functional collaboration in a matrixed environment.
• Comprehensive medical, dental, vision, and other insurance benefits for employees and families.
• Retirement benefits including a 401(k), paid holidays, vacation, compassionate leave, and sick days.
• Inclusive environment that values diverse perspectives and respectful challenge.
• Visa sponsorship is not available.