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10 дней назад

Curricular Internship - Soranzo Lab (Population & Medical Genomics)

Формат работы
onsite
Тип работы
fulltime
Грейд
trainee
Английский
b2
Страна
Italy
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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TL;DR
Curricular Internship - Soranzo Lab (Population & Medical Genomics) (Pangenome Genotyping): Developing alignment-free tools and algorithms to recruit locus-specific reads from raw sequencing data for complex genomic loci with an accent on k-mer data structures, graph-based pangenomics, and high-performance scientific programming. Focus on building a reference-agnostic genotyping front-end, benchmarking modern human and ancient DNA datasets, and optimizing large-scale sequencing workflows.

Location: Based in Milan, Italy

Company

hirify.global is a life science research institute focused on biomedical discovery through computational, genomic, functional, and immunological research.

What you will do

  • Develop alignment-free methods to recruit locus-specific reads directly from raw sequencing data.
  • Build or extend tools for identifying specific k-mers from pangenomic assemblies and sequenced samples.
  • Implement efficient algorithms for extracting reads from FASTQ files for complex loci such as MHC and AMY1.
  • Build and integrate a fast, reference-agnostic front-end for the COSIGT/PANVAR pangenome genotyping pipeline.
  • Benchmark performance across modern human populations and ancient DNA datasets.
  • Present progress and scientific findings in regular research group meetings.

Requirements

  • Currently enrolled in an MSc program in Bioinformatics, Computational Biology, Computer Science, Biotechnology, or a related discipline.
  • Strong programming skills in Python and/or Go or C++.
  • Familiarity with k-mer data structures and sequence formats including FASTQ and BAM.
  • Working knowledge of Unix environments and Git.
  • Good written and spoken English.
  • Strong analytical, problem-solving, communication, teamwork, organizational, and independent-working skills.

Nice to have

  • Background or interest in pangenomics, sequence alignment, and graph algorithms.
  • Experience with complex structural variation or ancient DNA.

Culture & Benefits

  • Interdisciplinary and international research environment.
  • Close supervision and mentoring from experienced scientists.
  • Access to scientific seminars, training initiatives, networking opportunities, and learning opportunities.
  • Internship duration: 12 months.
  • One position available.

Hiring process

  • Submit a CV and a motivation letter in English.
  • Application deadline: October 29, 2026.

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