Technical Operations Senior Engineer (Oncolytic Virus Manufacturing)

Location: Framingham, Massachusetts, United States; 5-day on-site expectation

Salary: $146,000–$189,000 annual base pay

Company

hirify.global is a biotechnology company developing oncolytic immunotherapies based on its proprietary HSV-1 platform to activate systemic anti-tumor immune responses.

What you will do

• Provide technical support and cross-functional leadership for oncolytic virus drug substance, drug product, and secondary packaging manufacturing.
• Manage technology transfer, post-transfer manufacturing support, commercialization, process validation, and manufacturing readiness activities.
• Troubleshoot product processing technologies and equipment, including bioreactors, TFF systems, chromatography systems, and filling machines.
• Lead CAPA, change control, deviation resolution, continuous process verification, and process improvement activities.
• Conduct process optimization, data and trend evaluation, risk assessments, and mitigation planning.
• Author technical documentation and support regulatory filings, audits, supplier changes, and cross-functional manufacturing execution.

Requirements

• Master’s degree in chemical or biomedical engineering with 4–6 years of related experience, or bachelor’s degree with 6–8 years of related experience.
• At least 4 years of experience in biologics drug substance or drug product process development or manufacturing support.
• Experience with single-use manufacturing technologies, manufacturing equipment troubleshooting, and commercial manufacturing in a regulated environment.
• Experience with process characterization, Process Performance Qualification, Continued Process Verification, commercialization, and process validation lifecycle activities.
• Experience using FMEA, risk analysis, and change impact assessment methods.
• Strong technical writing, data analysis, communication, organizational, and cross-functional collaboration skills.

Culture & Benefits

• Purpose-driven work focused on transforming cancer treatment and improving patient outcomes.
• Medical, dental, and vision insurance.
• 401(k) match, flexible time off, and paid holidays including a year-end shutdown.
• Eligibility for an annual performance incentive bonus, new-hire equity, and ongoing performance-based equity.
• Commitment to safe work practices, technical development, and an inclusive equal-opportunity workplace.