Executive Director, Clinical Pharmacology/Pharmacometrics

Location: Remote, United States; periodic travel required.

Annual base salary: $287,980–$346,060 in New York City, Boston, and the San Francisco Bay Area; $261,800–$314,600 in Salt Lake City and other U.S. locations. Annual bonus, equity compensation, and benefits are also available.

Company

hirify.global is a clinical-stage TechBio company using AI, biology, chemistry, and clinical development to advance investigational medicines for oncology, rare disease, neuroscience, immunology, and other areas of unmet need.

What you will do

• Lead clinical pharmacology and pharmacometric strategy and execution across clinical development programs.
• Develop modeling and simulation strategies to support product development and accelerate decision-making.
• Provide clinical pharmacology input into Phase 1–3 studies and dedicated clinical pharmacology studies.
• Prepare clinical pharmacology sections for Investigator’s Brochures, INDs, NDAs, and other regulatory submissions.
• Represent clinical pharmacology in regulatory interactions and meetings with health authorities.
• Collaborate with clinical development, DMPK, translational modeling, toxicology, preclinical, and due diligence teams.

Requirements

• Ph.D. in Pharmaceutical Sciences, Pharmacokinetics, or a related discipline; M.D. with clinical pharmacology expertise; or Pharm.D. with a clinical pharmacology fellowship.
• 10+ years of experience in biotech or pharmaceutical drug development.
• Experience leading clinical pharmacology aspects of drug development and managing PK, PK-PD, and PK-safety analyses.
• Experience with non-compartmental analysis, population PK modeling, PK-PD modeling, and simulations for dose selection and exposure-response or exposure-safety analyses.
• Proficiency with WinNonlin, Monolix, NONMEM, R, or other modeling software.
• Experience preparing regulatory submissions, responding to agency questions, and attending regulatory meetings.

Nice to have

• Experience in oncology.

Culture & Benefits

• Remote work arrangement with periodic travel.
• Annual bonus and equity compensation.
• Comprehensive benefits package.
• Cross-functional collaboration across discovery and development teams.
• Values emphasize scientific integrity, ownership, adaptability, urgency, and direct collaboration.